Publications

Link to publications by PSOC@Penn investigators since 2015 (Pubmed)

Progerin phosphorylation in interphase is lower and less mechanosensitive than lamin-A,C in iPS-derived mesenchymal stem cells. Cho S, Abbas A, Irianto J, Ivanovska I, Xia Y, Tewari M, Discher DE. Nucleus. 2018 Apr 5:1-32. doi: 10.1080/19491034.2018.1460185. [Epub ahead of print]
BILIARY ATRESIA: Clinical and Research Challenges for the 21(st) Century. Bezerra JA, Wells RG, Mack CL, Karpen SJ, Hoofnagle JH, Doo E, Sokol RJ. Hepatology. 2018 Mar 31. doi: 10.1002/hep.29905. [Epub ahead of print]
Nanoscale Rheology and Anisotropic Diffusion Using Single Gold Nanorod Probes. Molaei M, Atefi E, Crocker JC. Phys Rev Lett. 2018 Mar 16;120(11):118002. doi: 10.1103/PhysRevLett.120.118002.
Structure and Distribution of an Unrecognized Interstitium in Human Tissues. Benias PC, Wells RG, Sackey-Aboagye B, Klavan H, Reidy J, Buonocore D, Miranda M, Kornacki S, Wayne M, Carr-Locke DL, Theise ND. Sci Rep. 2018 Mar 27;8(1):4947. doi: 10.1038/s41598-018-23062-6.
Similar Biophysical Abnormalities in Glomeruli and Podocytes from Two Distinct Models. Embry AE, Liu Z, Henderson JM, Byfield FJ, Liu L, Yoon J, Wu Z, Cruz K, Moradi S, Gillombardo CB, Hussain RZ, Doelger R, Stuve O, Chang AN, Janmey PA, Bruggeman LA, Miller RT. J Am Soc Nephrol. 2018 Mar 23. pii: ASN.2017050475. doi: 10.1681/ASN.2017050475. [Epub ahead of print]
Prediction of optimal structural water concentration for maximized performance in tunnel manganese oxide electrodes. Frey NC, Byles BW, Kumar H, Er D, Pomerantseva E, Shenoy VB. Phys Chem Chem Phys. 2018 Apr 4;20(14):9480-9487. doi: 10.1039/C8CP00761F.
Cost/Benefit of Hepatitis C Treatment: It Does Not End with SVR. Kaplan DE. Dig Dis Sci. 2018 Mar 17. doi: 10.1007/s10620-018-5014-7. [Epub ahead of print] No abstract available.
Glial Tissue Mechanics and Mechanosensing by Glial Cells. Pogoda K, Janmey PA. Front Cell Neurosci. 2018 Feb 21;12:25. doi: 10.3389/fncel.2018.00025. eCollection 2018. Review.
Matching material and cellular timescales maximizes cell spreading on viscoelastic substrates. Gong Z, Szczesny SE, Caliari SR, Charrier EE, Chaudhuri O, Cao X, Lin Y, Mauck RL, Janmey PA, Burdick JA, Shenoy VB. Proc Natl Acad Sci U S A. 2018 Mar 20;115(12):E2686-E2695. doi: 10.1073/pnas.1716620115. Epub 2018 Mar 5.
Transarterial Chemoembolization within First 3 Months of Sorafenib Initiation Improves Overall Survival in Hepatocellular Carcinoma: A Retrospective, Multi-Institutional Study with Propensity Matching. Kaplan DE, Mehta R, D’Addeo K, Gade TP, Taddei TH. J Vasc Interv Radiol. 2018 Apr;29(4):540-549.e4. doi: 10.1016/j.jvir.2017.11.033. Epub 2018 Feb 22.
Maturation State and Matrix Microstructure Regulate Interstitial Cell Migration in Dense Connective Tissues. Qu F, Li Q, Wang X, Cao X, Zgonis MH, Esterhai JL, Shenoy VB, Han L, Mauck RL. Sci Rep. 2018 Feb 19;8(1):3295. doi: 10.1038/s41598-018-21212-4.
Direct Quantitative Monitoring of Homology-Directed DNA Repair of Damaged Telomeres. Verma P, Dilley RL, Gyparaki MT, Greenberg RA. Methods Enzymol. 2018;600:107-134. doi: 10.1016/bs.mie.2017.11.010. Epub 2018 Feb 1.
Rare Cell Detection by Single-Cell RNA Sequencing as Guided by Single-Molecule RNA FISH. Torre E, Dueck H, Shaffer S, Gospocic J, Gupte R, Bonasio R, Kim J, Murray J, Raj A. Cell Syst. 2018 Feb 28;6(2):171-179.e5. doi: 10.1016/j.cels.2018.01.014. Epub 2018 Feb 14.
Filomicelles Deliver a Chemo-Differentiation Combination of Paclitaxel and Retinoic Acid That Durably Represses Carcinomas in Liver to Prolong Survival. Nair PR, Alvey C, Jin X, Irianto J, Ivanovska I, Discher DE. Bioconjug Chem. 2018 Mar 1. doi: 10.1021/acs.bioconjchem.7b00816. [Epub ahead of print]
Kinetics of PTEN-mediated PI(3,4,5)P3 hydrolysis on solid supported membranes. Liu C, Deb S, Ferreira VS, Xu E, Baumgart T. PLoS One. 2018 Feb 15;13(2):e0192667. doi: 10.1371/journal.pone.0192667. eCollection 2018.
Cellular and Molecular Mechanisms of Centromere Drive. Lampson MA, Black BE. Cold Spring Harb Symp Quant Biol. 2018 Feb 12. pii: 034298. doi: 10.1101/sqb.2017.82.034298. [Epub ahead of print] Erratum in: Cold Spring Harb Symp Quant Biol. 2018 Feb 26;:.
Enhanced B-cell differentiation driven by advanced cirrhosis resulting in hyperglobulinemia. Doi H, Hayashi E, Arai J, Tojo M, Morikawa K, Eguchi J, Ito T, Kanto T, Kaplan DE, Yoshida H. J Gastroenterol Hepatol. 2018 Feb 10. doi: 10.1111/jgh.14123. [Epub ahead of print]
Integrins Modulate T Cell Receptor Signaling by Constraining Actin Flow at the Immunological Synapse. Jankowska KI, Williamson EK, Roy NH, Blumenthal D, Chandra V, Baumgart T, Burkhardt JK. Front Immunol. 2018 Jan 18;9:25. doi: 10.3389/fimmu.2018.00025. eCollection 2018.
Mechanisms of Plastic Deformation in Collagen Networks Induced by Cellular Forces. Ban E, Franklin JM, Nam S, Smith LR, Wang H, Wells RG, Chaudhuri O, Liphardt JT, Shenoy VB. Biophys J. 2018 Jan 23;114(2):450-461. doi: 10.1016/j.bpj.2017.11.3739.
Targeting polyelectrolyte networks in purulent body fluids to modulate bactericidal properties of some antibiotics. Bucki R, DurnaÅ› B, WÄ…tek M, Piktel E, Cruz K, Wolak P, Savage PB, Janmey PA. Infect Drug Resist. 2018 Jan 11;11:77-86. doi: 10.2147/IDR.S145337. eCollection 2018.
Control of cell morphology and differentiation by substrates with independently tunable elasticity and viscous dissipation. Charrier EE, Pogoda K, Wells RG, Janmey PA. Nat Commun. 2018 Jan 31;9(1):449. doi: 10.1038/s41467-018-02906-9.
Auxetic metamaterials from disordered networks. Reid DR, Pashine N, Wozniak JM, Jaeger HM, Liu AJ, Nagel SR, de Pablo JJ. Proc Natl Acad Sci U S A. 2018 Feb 13;115(7):E1384-E1390. doi: 10.1073/pnas.1717442115. Epub 2018 Jan 30.
Sorafenib prescribed by gastroenterologists and hepatologists for hepatocellular carcinoma: A retrospective, multi-institutional cohort study. Kaplan DE, Mehta R, D’Addeo K, Valderrama A, Taddei TH; Sorafenib for Hepatocellular carcinomA in VEterans (SHAVE) Study Investigators.. Medicine (Baltimore). 2018 Jan;97(4):e9757. doi: 10.1097/MD.0000000000009757.
The fibronectin ED-A domain enhances recruitment of latent TGF-β-binding protein-1 to the fibroblast matrix. Klingberg F, Chau G, Walraven M, Boo S, Koehler A, Chow ML, Olsen AL, Im M, Lodyga M, Wells RG, White ES, Hinz B. J Cell Sci. 2018 Mar 1;131(5). pii: jcs201293. doi: 10.1242/jcs.201293.
Synthesis and Structure-Activity Relationship Study of Biliatresone, a Plant Isoflavonoid That Causes Biliary Atresia. Estrada MA, Zhao X, Lorent K, Kriegermeier A, Nagao SA, Berritt S, Wells RG, Pack M, Winkler JD. ACS Med Chem Lett. 2017 Dec 14;9(1):61-64. doi: 10.1021/acsmedchemlett.7b00479. eCollection 2018 Jan 11.
Patterns of Discordance Between Pretransplant Imaging Stage of Hepatocellular Carcinoma and Posttransplant Pathologic Stage: A Contemporary Appraisal of the Milan Criteria. Ecker BL, Hoteit MA, Forde KA, Hsu CC, Reddy KR, Furth EE, Siegelman ES, Habibollahi P, Ben-Josef E, Porrett PM, Abt PL, Shaked A, Olthoff KM, Levine MH. Transplantation. 2018 Apr;102(4):648-655. doi: 10.1097/TP.0000000000002056.
Convergence to Cure Cancer through Research: A Message from the New Editor-in-Chief. Dang CV. Cancer Res. 2018 Jan 1;78(1):3-4. doi: 10.1158/0008-5472.CAN-17-3771. No abstract available.
Combination of Neoadjuvant Transcatheter Arterial Chemoembolization and Orthotopic Liver Transplantation for the Treatment of Cirrhotomimetic Hepatocellular Carcinoma. Habibollahi P, Shamchi SP, Tondon R, Ecker BL, Gade TP, Hunt S, Soulen MC, Furth EE, Levine MH, Nadolski G. J Vasc Interv Radiol. 2018 Feb;29(2):237-243. doi: 10.1016/j.jvir.2017.09.008. Epub 2017 Dec 6.
Interaction Heterogeneity can Favorably Impact Colloidal Crystal Nucleation. Jenkins IC, Crocker JC, Sinno T. Phys Rev Lett. 2017 Oct 27;119(17):178002. doi: 10.1103/PhysRevLett.119.178002. Epub 2017 Oct 23.
Instabilities of Jammed Packings of Frictionless Spheres Under Load. Xu N, Liu AJ, Nagel SR. Phys Rev Lett. 2017 Nov 24;119(21):215502. doi: 10.1103/PhysRevLett.119.215502. Epub 2017 Nov 20.
Stem Cell Differentiation is Regulated by Extracellular Matrix Mechanics. Smith LR, Cho S, Discher DE. Physiology (Bethesda). 2018 Jan 1;33(1):16-25. doi: 10.1152/physiol.00026.2017. Review.
Future cancer research priorities in the USA: a Lancet Oncology Commission. Jaffee EM, Dang CV, Agus DB, Alexander BM, Anderson KC, Ashworth A, Barker AD, Bastani R, Bhatia S, Bluestone JA, Brawley O, Butte AJ, Coit DG, Davidson NE, Davis M, DePinho RA, Diasio RB, Draetta G, Frazier AL, Futreal A, Gambhir SS, Ganz PA, et al. Lancet Oncol. 2017 Nov;18(11):e653-e706. doi: 10.1016/S1470-2045(17)30698-8. Epub 2017 Oct 31. Review.
Toward a Mechanistic Understanding of Vertical Growth of van der Waals Stacked 2D Materials: A Multiscale Model and Experiments. Ye H, Zhou J, Er D, Price CC, Yu Z, Liu Y, Lowengrub J, Lou J, Liu Z, Shenoy VB. ACS Nano. 2017 Dec 26;11(12):12780-12788. doi: 10.1021/acsnano.7b07604. Epub 2017 Dec 11.
Structure-property relationships from universal signatures of plasticity in disordered solids. Cubuk ED, Ivancic RJS, Schoenholz SS, Strickland DJ, Basu A, Davidson ZS, Fontaine J, Hor JL, Huang YR, Jiang Y, Keim NC, Koshigan KD, Lefever JA, Liu T, Ma XG, Magagnosc DJ, Morrow E, Ortiz CP, Rieser JM, Shavit A, Still T, Xu Y, et al. Science. 2017 Nov 24;358(6366):1033-1037. doi: 10.1126/science.aai8830.
The notch pathway is activated in neoplastic progression in esophageal squamous cell carcinoma. Lubin DJ, Mick R, Shroff SG, Stashek K, Furth EE. Hum Pathol. 2018 Feb;72:66-70. doi: 10.1016/j.humpath.2017.11.004. Epub 2017 Nov 12.
Erythropoietic protoporphyria in an adult with sequential liver and hematopoietic stem cell transplantation: A case report. Windon AL, Tondon R, Singh N, Abu-Gazala S, Porter DL, Russell JE, Cook C, Lander E, Smith G, Olthoff KM, Shaked A, Hoteit M, Furth EE, Serper M. Am J Transplant. 2018 Mar;18(3):745-749. doi: 10.1111/ajt.14581. Epub 2017 Dec 9.
Excess area dependent scaling behavior of nano-sized membrane tethers. Ramakrishnan N, Sreeja KK, Roychoudhury A, Eckmann DM, Ayyaswamy PS, Baumgart T, Pucadyil T, Patil S, Weaver VM, Radhakrishnan R. Phys Biol. 2018 Jan 11;15(2):026002. doi: 10.1088/1478-3975/aa9905.
Newfound sex differences in axonal structure underlie differential outcomes from in vitro traumatic axonal injury. Dollé JP, Jaye A, Anderson SA, Ahmadzadeh H, Shenoy VB, Smith DH. Exp Neurol. 2018 Feb;300:121-134. doi: 10.1016/j.expneurol.2017.11.001. Epub 2017 Nov 22.
Spindle asymmetry drives non-Mendelian chromosome segregation. Akera T, Chmátal L, Trimm E, Yang K, Aonbangkhen C, Chenoweth DM, Janke C, Schultz RM, Lampson MA. Science. 2017 Nov 3;358(6363):668-672. doi: 10.1126/science.aan0092.
Mechanical Properties of the Cytoskeleton and Cells. Pegoraro AF, Janmey P, Weitz DA. Cold Spring Harb Perspect Biol. 2017 Nov 1;9(11). pii: a022038. doi: 10.1101/cshperspect.a022038. Review.
Genome variation across cancers scales with tissue stiffness – an invasion-mutation mechanism and implications for immune cell infiltration. Pfeifer CR, Alvey CM, Irianto J, Discher DE. Curr Opin Syst Biol. 2017 Apr;2:103-114. doi: 10.1016/j.coisb.2017.04.005. Epub 2017 Apr 27.
Intercellular mRNA trafficking via membrane nanotube-like extensions in mammalian cells. Haimovich G, Ecker CM, Dunagin MC, Eggan E, Raj A, Gerst JE, Singer RH. Proc Natl Acad Sci U S A. 2017 Nov 14;114(46):E9873-E9882. doi: 10.1073/pnas.1706365114. Epub 2017 Oct 24.
EGFR Ligands Differentially Stabilize Receptor Dimers to Specify Signaling Kinetics. Freed DM, Bessman NJ, Kiyatkin A, Salazar-Cavazos E, Byrne PO, Moore JO, Valley CC, Ferguson KM, Leahy DJ, Lidke DS, Lemmon MA. Cell. 2017 Oct 19;171(3):683-695.e18. doi: 10.1016/j.cell.2017.09.017. Epub 2017 Oct 5.
Replication defective viral genomes exploit a cellular pro-survival mechanism to establish paramyxovirus persistence. Xu J, Sun Y, Li Y, Ruthel G, Weiss SR, Raj A, Beiting D, López CB. Nat Commun. 2017 Oct 6;8(1):799. doi: 10.1038/s41467-017-00909-6.
Two mechanisms coordinate the recruitment of the chromosomal passenger complex to the plane of cell division. Landino J, Norris SR, Li M, Ballister ER, Lampson MA, Ohi R. Mol Biol Cell. 2017 Dec 1;28(25):3634-3646. doi: 10.1091/mbc.E17-06-0399. Epub 2017 Sep 27.
Period proliferation in periodic states in cyclically sheared jammed solids. Lavrentovich MO, Liu AJ, Nagel SR. Phys Rev E. 2017 Aug;96(2-1):020101. doi: 10.1103/PhysRevE.96.020101. Epub 2017 Aug 10.
Coordinated increase of nuclear tension and lamin-A with matrix stiffness outcompetes lamin-B receptor that favors soft tissue phenotypes. Buxboim A, Irianto J, Swift J, Athirasala A, Shin JW, Rehfeldt F, Discher DE. Mol Biol Cell. 2017 Nov 7;28(23):3333-3348. doi: 10.1091/mbc.E17-06-0393. Epub 2017 Sep 20.
Group 1 Innate Lymphoid Cell Lineage Identity Is Determined by a cis-Regulatory Element Marked by a Long Non-coding RNA. Mowel WK, McCright SJ, Kotzin JJ, Collet MA, Uyar A, Chen X, DeLaney A, Spencer SP, Virtue AT, Yang E, Villarino A, Kurachi M, Dunagin MC, Pritchard GH, Stein J, Hughes C, Fonseca-Pereira D, Veiga-Fernandes H, Raj A, Kambayashi T, Brodsky IE, O’Shea JJ, et al. Immunity. 2017 Sep 19;47(3):435-449.e8. doi: 10.1016/j.immuni.2017.08.012.
Tumor-associated B-cells induce tumor heterogeneity and therapy resistance. Somasundaram R, Zhang G, Fukunaga-Kalabis M, Perego M, Krepler C, Xu X, Wagner C, Hristova D, Zhang J, Tian T, Wei Z, Liu Q, Garg K, Griss J, Hards R, Maurer M, Hafner C, Mayerhöfer M, Karanikas G, Jalili A, Bauer-Pohl V, Weihsengruber F, et al. Nat Commun. 2017 Sep 19;8(1):607. doi: 10.1038/s41467-017-00452-4.
Disconnecting structure and dynamics in glassy thin films. Sussman DM, Schoenholz SS, Cubuk ED, Liu AJ. Proc Natl Acad Sci U S A. 2017 Oct 3;114(40):10601-10605. doi: 10.1073/pnas.1703927114. Epub 2017 Sep 19.
Mitotic transcription and waves of gene reactivation during mitotic exit. Palozola KC, Donahue G, Liu H, Grant GR, Becker JS, Cote A, Yu H, Raj A, Zaret KS. Science. 2017 Oct 6;358(6359):119-122. doi: 10.1126/science.aal4671. Epub 2017 Sep 14.
Rupture Dynamics and Chromatin Herniation in Deformed Nuclei. Deviri D, Discher DE, Safran SA. Biophys J. 2017 Sep 5;113(5):1060-1071. doi: 10.1016/j.bpj.2017.07.014.
Starting Dose of Sorafenib for the Treatment of Hepatocellular Carcinoma: A Retrospective, Multi-Institutional Study. Reiss KA, Yu S, Mamtani R, Mehta R, D’Addeo K, Wileyto EP, Taddei TH, Kaplan DE. J Clin Oncol. 2017 Nov 1;35(31):3575-3581. doi: 10.1200/JCO.2017.73.8245. Epub 2017 Sep 5.
A novel role for ceramide synthase 6 in mouse and human alcoholic steatosis. Williams B, Correnti J, Oranu A, Lin A, Scott V, Annoh M, Beck J, Furth E, Mitchell V, Senkal CE, Obeid L, Carr RM. FASEB J. 2018 Jan;32(1):130-142. doi: 10.1096/fj.201601142R. Epub 2017 Sep 1.
Soft Substrates Containing Hyaluronan Mimic the Effects of Increased Stiffness on Morphology, Motility, and Proliferation of Glioma Cells. Pogoda K, Bucki R, Byfield FJ, Cruz K, Lee T, Marcinkiewicz C, Janmey PA. Biomacromolecules. 2017 Oct 9;18(10):3040-3051. doi: 10.1021/acs.biomac.7b00324. Epub 2017 Sep 14.
Cell Biology of Cheating-Transmission of Centromeres and Other Selfish Elements Through Asymmetric Meiosis. Chmátal L, Schultz RM, Black BE, Lampson MA. Prog Mol Subcell Biol. 2017;56:377-396. doi: 10.1007/978-3-319-58592-5_16.
Optimal Contractile Forces for a Mesenchymal Engine. Discher DE, Dooling LJ. Dev Cell. 2017 Aug 21;42(4):313-315. doi: 10.1016/j.devcel.2017.08.005.
A magnetic micropore chip for rapid (<1 hour) unbiased circulating tumor cell isolation and in situ RNA analysis. Ko J, Bhagwat N, Yee SS, Black T, Redlinger C, Romeo J, O’Hara M, Raj A, Carpenter EL, Stanger BZ, Issadore D. Lab Chip. 2017 Sep 12;17(18):3086-3096. doi: 10.1039/c7lc00703e.
Optogenetic control of kinetochore function. Zhang H, Aonbangkhen C, Tarasovetc EV, Ballister ER, Chenoweth DM, Lampson MA. Nat Chem Biol. 2017 Oct;13(10):1096-1101. doi: 10.1038/nchembio.2456. Epub 2017 Aug 14.
Centromere inheritance through the germline. Das A, Smoak EM, Linares-Saldana R, Lampson MA, Black BE. Chromosoma. 2017 Oct;126(5):595-604. doi: 10.1007/s00412-017-0640-y. Epub 2017 Aug 8. Review.
Janus dendrimersomes coassembled from fluorinated, hydrogenated, and hybrid Janus dendrimers as models for cell fusion and fission. Xiao Q, Sherman SE, Wilner SE, Zhou X, Dazen C, Baumgart T, Reed EH, Hammer DA, Shinoda W, Klein ML, Percec V. Proc Natl Acad Sci U S A. 2017 Aug 22;114(34):E7045-E7053. doi: 10.1073/pnas.1708380114. Epub 2017 Aug 7.
Janus Monolayer Transition-Metal Dichalcogenides. Zhang J, Jia S, Kholmanov I, Dong L, Er D, Chen W, Guo H, Jin Z, Shenoy VB, Shi L, Lou J. ACS Nano. 2017 Aug 22;11(8):8192-8198. doi: 10.1021/acsnano.7b03186. Epub 2017 Aug 9.
Diverse BRCA1 and BRCA2 Reversion Mutations in Circulating Cell-Free DNA of Therapy-Resistant Breast or Ovarian Cancer. Weigelt B, Comino-Méndez I, de Bruijn I, Tian L, Meisel JL, García-Murillas I, Fribbens C, Cutts R, Martelotto LG, Ng CKY, Lim RS, Selenica P, Piscuoglio S, Aghajanian C, Norton L, Murali R, Hyman DM, Borsu L, Arcila ME, Konner J, Reis-Filho JS, Greenberg RA, et al. Clin Cancer Res. 2017 Nov 1;23(21):6708-6720. doi: 10.1158/1078-0432.CCR-17-0544. Epub 2017 Aug 1.
Mitotic progression following DNA damage enables pattern recognition within micronuclei. Harding SM, Benci JL, Irianto J, Discher DE, Minn AJ, Greenberg RA. Nature. 2017 Aug 24;548(7668):466-470. doi: 10.1038/nature23470. Epub 2017 Jul 31.
Expanded Satellite Repeats Amplify a Discrete CENP-A Nucleosome Assembly Site on Chromosomes that Drive in Female Meiosis. Iwata-Otsubo A, Dawicki-McKenna JM, Akera T, Falk SJ, Chmátal L, Yang K, Sullivan BA, Schultz RM, Lampson MA, Black BE. Curr Biol. 2017 Aug 7;27(15):2365-2373.e8. doi: 10.1016/j.cub.2017.06.069. Epub 2017 Jul 27.
Healthcare Costs Related to Treatment of Hepatocellular Carcinoma Among Veterans With Cirrhosis in the United States. Kaplan DE, Chapko MK, Mehta R, Dai F, Skanderson M, Aytaman A, Baytarian M, D’Addeo K, Fox R, Hunt K, Pocha C, Valderrama A, Taddei TH; VOCAL Study Group.. Clin Gastroenterol Hepatol. 2018 Jan;16(1):106-114.e5. doi: 10.1016/j.cgh.2017.07.024. Epub 2017 Jul 26.
T-bet-expressing B cells during HIV and HCV infections. Knox JJ, Kaplan DE, Betts MR. Cell Immunol. 2017 Nov;321:26-34. doi: 10.1016/j.cellimm.2017.04.012. Epub 2017 Jul 11. Review.
Does Maternity Care Coordination Influence Perinatal Health Care Utilization? Evidence from North Carolina. Hillemeier MM, Domino ME, Wells R, Goyal RK, Kum HC, Cilenti D, Basu A. Health Serv Res. 2017 Jul 20. doi: 10.1111/1475-6773.12742. [Epub ahead of print]
Large In-Plane and Vertical Piezoelectricity in Janus Transition Metal Dichalchogenides. Dong L, Lou J, Shenoy VB. ACS Nano. 2017 Aug 22;11(8):8242-8248. doi: 10.1021/acsnano.7b03313. Epub 2017 Jul 17.
Nuclear Acetyl-CoA Production by ACLY Promotes Homologous Recombination. Sivanand S, Rhoades S, Jiang Q, Lee JV, Benci J, Zhang J, Yuan S, Viney I, Zhao S, Carrer A, Bennett MJ, Minn AJ, Weljie AM, Greenberg RA, Wellen KE. Mol Cell. 2017 Jul 20;67(2):252-265.e6. doi: 10.1016/j.molcel.2017.06.008. Epub 2017 Jul 6.
Persistence of exhaustion in cured hep C. Kaplan DE. Blood. 2017 Jul 6;130(1):4. doi: 10.1182/blood-2017-05-786368. No abstract available.
SIRPA-Inhibited, Marrow-Derived Macrophages Engorge, Accumulate, and Differentiate in Antibody-Targeted Regression of Solid Tumors. Alvey CM, Spinler KR, Irianto J, Pfeifer CR, Hayes B, Xia Y, Cho S, Dingal PCPD, Hsu J, Smith L, Tewari M, Discher DE. Curr Biol. 2017 Jul 24;27(14):2065-2077.e6. doi: 10.1016/j.cub.2017.06.005. Epub 2017 Jun 29.
Extracranial Aneurysms in 2 Patients with Autosomal Recessive Polycystic Kidney Disease. Elchediak DS, Cahill AM, Furth EE, Kaplan BS, Hartung EA. Case Rep Nephrol Dial. 2017 May 2;7(2):34-42. doi: 10.1159/000475492. eCollection 2017 May-Aug.
Rare cell variability and drug-induced reprogramming as a mode of cancer drug resistance. Shaffer SM, Dunagin MC, Torborg SR, Torre EA, Emert B, Krepler C, Beqiri M, Sproesser K, Brafford PA, Xiao M, Eggan E, Anastopoulos IN, Vargas-Garcia CA, Singh A, Nathanson KL, Herlyn M, Raj A. Nature. 2017 Jun 15;546(7658):431-435. doi: 10.1038/nature22794. Epub 2017 Jun 7. Erratum in: Nature. 2018 Feb 21;:.
Visualizing adenosine-to-inosine RNA editing in single mammalian cells. Mellis IA, Gupte R, Raj A, Rouhanifard SH. Nat Methods. 2017 Aug;14(8):801-804. doi: 10.1038/nmeth.4332. Epub 2017 Jun 12.
Elastic-Fluid Model for DNA Damage and Mutation from Nuclear Fluid Segregation Due to Cell Migration. Bennett RR, Pfeifer CR, Irianto J, Xia Y, Discher DE, Liu AJ. Biophys J. 2017 Jun 6;112(11):2271-2279. doi: 10.1016/j.bpj.2017.04.037.
Mechanosensing of matrix by stem cells: From matrix heterogeneity, contractility, and the nucleus in pore-migration to cardiogenesis and muscle stem cells in vivo. Smith L, Cho S, Discher DE. Semin Cell Dev Biol. 2017 Nov;71:84-98. doi: 10.1016/j.semcdb.2017.05.025. Epub 2017 Jun 3. Review.
Cross-linked matrix rigidity and soluble retinoids synergize in nuclear lamina regulation of stem cell differentiation. Ivanovska IL, Swift J, Spinler K, Dingal D, Cho S, Discher DE. Mol Biol Cell. 2017 Jul 7;28(14):2010-2022. doi: 10.1091/mbc.E17-01-0010. Epub 2017 May 31.
Tunable Magnetism and Transport Properties in Nitride MXenes. Kumar H, Frey NC, Dong L, Anasori B, Gogotsi Y, Shenoy VB. ACS Nano. 2017 Aug 22;11(8):7648-7655. doi: 10.1021/acsnano.7b02578. Epub 2017 Jun 7.
Spray stability of self-assembled filaments for delivery. Mahmud A, Harada T, Rajagopal K, Christian DA, Nair P, Murphy R, Discher DE. J Control Release. 2017 Oct 10;263:162-171. doi: 10.1016/j.jconrel.2017.05.026. Epub 2017 May 24.
Matrix Mechanosensing: From Scaling Concepts in ‘Omics Data to Mechanisms in the Nucleus, Regeneration, and Cancer. Discher DE, Smith L, Cho S, Colasurdo M, García AJ, Safran S. Annu Rev Biophys. 2017 May 22;46:295-315. doi: 10.1146/annurev-biophys-062215-011206. Review.
Engineering macrophages to eat cancer: from “marker of self” CD47 and phagocytosis to differentiation. Alvey C, Discher DE. J Leukoc Biol. 2017 Jul;102(1):31-40. doi: 10.1189/jlb.4RI1216-516R. Epub 2017 May 18. Review.
Relative Initial Weight Is Associated with Improved Survival without Altering Tumor Latency in a Translational Rat Model of Diethylnitrosamine-Induced Hepatocellular Carcinoma and Transarterial Embolization. Kiefer RM, Hunt SJ, Pulido S, Pickup S, Furth EE, Soulen MC, Nadolski GJ, Gade TP. J Vasc Interv Radiol. 2017 Jul;28(7):1043-1050.e2. doi: 10.1016/j.jvir.2017.03.037. Epub 2017 May 9.
Identifying Patient and Provider-specific Gaps in Care Among Patients With Hepatitis B. Kushner T, Lam R, Gray DL, Kaplan DE, Serper M. J Clin Gastroenterol. 2017 Nov/Dec;51(10):900-906. doi: 10.1097/MCG.0000000000000806.
Effects of Sectoral Diversity on Community Coalition Processes and Outcomes. Brown LD, Wells R, Jones EC, Chilenski SM. Prev Sci. 2017 Jul;18(5):600-609. doi: 10.1007/s11121-017-0796-y.
Multiscale model predicts increasing focal adhesion size with decreasing stiffness in fibrous matrices. Cao X, Ban E, Baker BM, Lin Y, Burdick JA, Chen CS, Shenoy VB. Proc Natl Acad Sci U S A. 2017 Jun 6;114(23):E4549-E4555. doi: 10.1073/pnas.1620486114. Epub 2017 May 3.
Meiosis-specific proteins MEIOB and SPATA22 cooperatively associate with the single-stranded DNA-binding replication protein A complex and DNA double-strand breaks. Xu Y, Greenberg RA, Schonbrunn E, Wang PJ. Biol Reprod. 2017 May 1;96(5):1096-1104. doi: 10.1093/biolre/iox040.
Mps1 Regulates Kinetochore-Microtubule Attachment Stability via the Ska Complex to Ensure Error-Free Chromosome Segregation. Maciejowski J, Drechsler H, Grundner-Culemann K, Ballister ER, Rodriguez-Rodriguez JA, Rodriguez-Bravo V, Jones MJK, Foley E, Lampson MA, Daub H, McAinsh AD, Jallepalli PV. Dev Cell. 2017 Apr 24;41(2):143-156.e6. doi: 10.1016/j.devcel.2017.03.025.
Do Maternity Care Coordination Services Encourage Use of Behavioral Health Treatment among Pregnant Women on Medicaid? Shepherd-Banigan M, Domino ME, Wells R, Rutledge R, Hillemeier MM, Van Houtven CH. Womens Health Issues. 2017 Jul – Aug;27(4):449-455. doi: 10.1016/j.whi.2017.02.006. Epub 2017 Apr 17.
Dimerization of Tie2 mediated by its membrane-proximal FNIII domains. Moore JO, Lemmon MA, Ferguson KM. Proc Natl Acad Sci U S A. 2017 Apr 25;114(17):4382-4387. doi: 10.1073/pnas.1617800114. Epub 2017 Apr 10.
The BET Protein BRD2 Cooperates with CTCF to Enforce Transcriptional and Architectural Boundaries. Hsu SC, Gilgenast TG, Bartman CR, Edwards CR, Stonestrom AJ, Huang P, Emerson DJ, Evans P, Werner MT, Keller CA, Giardine B, Hardison RC, Raj A, Phillips-Cremins JE, Blobel GA. Mol Cell. 2017 Apr 6;66(1):102-116.e7. doi: 10.1016/j.molcel.2017.02.027.
Case-control analysis of truncating mutations in DNA damage response genes connects TEX15 and FANCD2 with hereditary breast cancer susceptibility. Mantere T, Tervasmäki A, Nurmi A, Rapakko K, Kauppila S, Tang J, Schleutker J, Kallioniemi A, Hartikainen JM, Mannermaa A, Nieminen P, Hanhisalo R, Lehto S, Suvanto M, Grip M, Jukkola-Vuorinen A, Tengström M, Auvinen P, Kvist A, Borg Å, Blomqvist C, Aittomäki K, et al. Sci Rep. 2017 Apr 6;7(1):681. doi: 10.1038/s41598-017-00766-9.
Neutrophils and Ly6Chi monocytes collaborate in generating an optimal cytokine response that protects against pulmonary Legionella pneumophila infection. Casson CN, Doerner JL, Copenhaver AM, Ramirez J, Holmgren AM, Boyer MA, Siddarthan IJ, Rouhanifard SH, Raj A, Shin S. PLoS Pathog. 2017 Apr 6;13(4):e1006309. doi: 10.1371/journal.ppat.1006309. eCollection 2017 Apr.
Comparing Child-Pugh, MELD, and FIB-4 to Predict Clinical Outcomes in Hepatitis C Virus-Infected Persons: Results From ERCHIVES. Butt AA, Ren Y, Lo Re V 3rd, Taddei TH, Kaplan DE. Clin Infect Dis. 2017 Jul 1;65(1):64-72. doi: 10.1093/cid/cix224.
FISHing Out the Details of CRISPR Genome Tracks. Coté AJ, Raj A. Biophys J. 2017 Mar 28;112(6):1045-1046. doi: 10.1016/j.bpj.2017.02.006. No abstract available.
Mechanotransduction in cancer. Chin L, Xia Y, Discher DE, Janmey PA. Curr Opin Chem Eng. 2016 Feb;11:77-84. doi: 10.1016/j.coche.2016.01.011. Epub 2016 Feb 16.
As a Nucleus Enters a Small Pore, Chromatin Stretches and Maintains Integrity, Even with DNA Breaks. Irianto J, Xia Y, Pfeifer CR, Greenberg RA, Discher DE. Biophys J. 2017 Feb 7;112(3):446-449. doi: 10.1016/j.bpj.2016.09.047. Epub 2016 Oct 27.
Association of Provider Specialty and Multidisciplinary Care With Hepatocellular Carcinoma Treatment and Mortality. Serper M, Taddei TH, Mehta R, D’Addeo K, Dai F, Aytaman A, Baytarian M, Fox R, Hunt K, Goldberg DS, Valderrama A, Kaplan DE; VOCAL Study Group.. Gastroenterology. 2017 Jun;152(8):1954-1964. doi: 10.1053/j.gastro.2017.02.040. Epub 2017 Mar 7.
Modulation of Hepatitis C Virus-Specific CD8 Effector T-Cell Function with Antiviral Effect in Infectious Hepatitis C Virus Coculture Model. Ojiro K, Qu X, Cho H, Park JJ, Vuidepot A, Lissin N, Molloy PE, Bennett A, Jakobsen BK, Kaplan DE, Riley JL, Chang KM. J Virol. 2017 Apr 28;91(10). pii: e02129-16. doi: 10.1128/JVI.02129-16. Print 2017 May 15.
Dimpled Polyhedral Colloids Formed by Colloidal Crystal Templating. Wang Y, McGinley JT, Crocker JC. Langmuir. 2017 Mar 28;33(12):3080-3087. doi: 10.1021/acs.langmuir.7b00202. Epub 2017 Mar 16.
Persistence-Driven Durotaxis: Generic, Directed Motility in Rigidity Gradients. Novikova EA, Raab M, Discher DE, Storm C. Phys Rev Lett. 2017 Feb 17;118(7):078103. doi: 10.1103/PhysRevLett.118.078103. Epub 2017 Feb 16.
Interplay of Platelet Contractility and Elasticity of Fibrin/Erythrocytes in Blood Clot Retraction. Tutwiler V, Wang H, Litvinov RI, Weisel JW, Shenoy VB. Biophys J. 2017 Feb 28;112(4):714-723. doi: 10.1016/j.bpj.2017.01.005.
Ischemia Induces Quiescence and Autophagy Dependence in Hepatocellular Carcinoma. Gade TPF, Tucker E, Nakazawa MS, Hunt SJ, Wong W, Krock B, Weber CN, Nadolski GJ, Clark TWI, Soulen MC, Furth EE, Winkler JD, Amaravadi RK, Simon MC. Radiology. 2017 Jun;283(3):702-710. doi: 10.1148/radiol.2017160728. Epub 2017 Mar 2.
Molecular and cytogenomic profiling of hepatic adenocarcinoma expressing inhibinA, a mimicker of neuroendocrine tumors: proposal to reclassify as “cholangioblastic variant of intrahepatic cholangiocarcinoma”. Braxton DR, Saxe D, Damjanov N, Stashek K, Shroff S, Morrissette JD, Tondon R, Furth EE. Hum Pathol. 2017 Apr;62:232-241. doi: 10.1016/j.humpath.2017.02.001. Epub 2017 Feb 21.
Designing allostery-inspired response in mechanical networks. Rocks JW, Pashine N, Bischofberger I, Goodrich CP, Liu AJ, Nagel SR. Proc Natl Acad Sci U S A. 2017 Mar 7;114(10):2520-2525. doi: 10.1073/pnas.1612139114. Epub 2017 Feb 21.
Modeling the two-way feedback between contractility and matrix realignment reveals a nonlinear mode of cancer cell invasion. Ahmadzadeh H, Webster MR, Behera R, Jimenez Valencia AM, Wirtz D, Weeraratna AT, Shenoy VB. Proc Natl Acad Sci U S A. 2017 Feb 28;114(9):E1617-E1626. doi: 10.1073/pnas.1617037114. Epub 2017 Feb 14.
Colloidal crystals with diamond symmetry at optical lengthscales. Wang Y, Jenkins IC, McGinley JT, Sinno T, Crocker JC. Nat Commun. 2017 Feb 13;8:14173. doi: 10.1038/ncomms14173.
One What? Why GI Researchers Should Know and Care About the One Health Initiative. Wells RG. Cell Mol Gastroenterol Hepatol. 2016 Sep 28;2(6):701-703. doi: 10.1016/j.jcmgh.2016.09.008. eCollection 2016 Nov. No abstract available.
The Scientific Conversation, Well Written. Wells RG. Cell Mol Gastroenterol Hepatol. 2016 May 30;2(4):385-386. doi: 10.1016/j.jcmgh.2016.05.009. eCollection 2016 Jul. No abstract available.
The Breadth of CMGH: Reflecting a Remarkable Field. Wells RG. Cell Mol Gastroenterol Hepatol. 2016 Jan 27;2(2):111. doi: 10.1016/j.jcmgh.2016.01.005. eCollection 2016 Mar. No abstract available.
Reply to the ‘Comment on “Spatial structure of states of self stress in jammed systems”‘ by E. Lerner, Soft Matter, 2017, 13, DOI. Sussman DM, Hexner D, Goodrich CP, Liu AJ. Soft Matter. 2017 Feb 22;13(8):1532-1533. doi: 10.1039/c6sm02496c.
Putting PHDs to work: PHF11 clears the way for EXO1 in double-strand break repair. Zahn KE, Greenberg RA. Genes Dev. 2017 Jan 1;31(1):3-5. doi: 10.1101/gad.295923.117.
Effect of wall-mediated hydrodynamic fluctuations on the kinetics of a Brownian nanoparticle. Yu HY, Eckmann DM, Ayyaswamy PS, Radhakrishnan R. Proc Math Phys Eng Sci. 2016 Dec;472(2196):20160397. doi: 10.1098/rspa.2016.0397.
Mixed outcomes for computational predictions. Dang CV. Elife. 2017 Jan 19;6. pii: e22661. doi: 10.7554/eLife.22661.
3D Functional Corneal Stromal Tissue Equivalent Based on Corneal Stromal Stem Cells and Multi-Layered Silk Film Architecture. Ghezzi CE, Marelli B, Omenetto FG, Funderburgh JL, Kaplan DL. PLoS One. 2017 Jan 18;12(1):e0169504. doi: 10.1371/journal.pone.0169504. eCollection 2017.
Mechanisms to Avoid and Correct Erroneous Kinetochore-Microtubule Attachments. Lampson MA, Grishchuk EL. Biology (Basel). 2017 Jan 5;6(1). pii: E1. doi: 10.3390/biology6010001. Review.
Mechanisms that determine nanocarrier targeting to healthy versus inflamed lung regions. Brenner JS, Bhamidipati K, Glassman PM, Ramakrishnan N, Jiang D, Paris AJ, Myerson JW, Pan DC, Shuvaev VV, Villa CH, Hood ED, Kiseleva R, Greineder CF, Radhakrishnan R, Muzykantov VR. Nanomedicine. 2017 May;13(4):1495-1506. doi: 10.1016/j.nano.2016.12.019. Epub 2017 Jan 5.
Marker of Self” CD47 on lentiviral vectors decreases macrophage-mediated clearance and increases delivery to SIRPA-expressing lung carcinoma tumors. Sosale NG, Ivanovska II, Tsai RK, Swift J, Hsu JW, Alvey CM, Zoltick PW, Discher DE. Mol Ther Methods Clin Dev. 2016 Dec 7;3:16080. doi: 10.1038/mtm.2016.80. eCollection 2016.
Site-Specific Fluorescence Polarization for Studying the Disaggregation of α-Synuclein Fibrils by Small Molecules. Haney CM, Cleveland CL, Wissner RF, Owei L, Robustelli J, Daniels MJ, Canyurt M, Rodriguez P, Ischiropoulos H, Baumgart T, Petersson EJ. Biochemistry. 2017 Feb 7;56(5):683-691. doi: 10.1021/acs.biochem.6b01060. Epub 2016 Nov 11.
Mechanosensing by the nucleus: From pathways to scaling relationships. Cho S, Irianto J, Discher DE. J Cell Biol. 2017 Feb;216(2):305-315. doi: 10.1083/jcb.201610042. Epub 2017 Jan 2. Review.
Curvature-Driven Migration of Colloids on Tense Lipid Bilayers. Li N, Sharifi-Mood N, Tu F, Lee D, Radhakrishnan R, Baumgart T, Stebe KJ. Langmuir. 2017 Jan 17;33(2):600-610. doi: 10.1021/acs.langmuir.6b03406. Epub 2016 Dec 30.
Rational Design of Two-Dimensional Metallic and Semiconducting Spintronic Materials Based on Ordered Double-Transition-Metal MXenes. Dong L, Kumar H, Anasori B, Gogotsi Y, Shenoy VB. J Phys Chem Lett. 2017 Jan 19;8(2):422-428. doi: 10.1021/acs.jpclett.6b02751. Epub 2017 Jan 5.
Computational Models for Nanoscale Fluid Dynamics and Transport Inspired by Nonequilibrium Thermodynamics. Radhakrishnan R, Yu HY, Eckmann DM, Ayyaswamy PS. J Heat Transfer. 2017 Mar;139(3):0330011-330019. doi: 10.1115/1.4035006. Epub 2016 Nov 22.
Relationship between local structure and relaxation in out-of-equilibrium glassy systems. Schoenholz SS, Cubuk ED, Kaxiras E, Liu AJ. Proc Natl Acad Sci U S A. 2017 Jan 10;114(2):263-267. doi: 10.1073/pnas.1610204114. Epub 2016 Dec 27.
DNA Damage Follows Repair Factor Depletion and Portends Genome Variation in Cancer Cells after Pore Migration. Irianto J, Xia Y, Pfeifer CR, Athirasala A, Ji J, Alvey C, Tewari M, Bennett RR, Harding SM, Liu AJ, Greenberg RA, Discher DE. Curr Biol. 2017 Jan 23;27(2):210-223. doi: 10.1016/j.cub.2016.11.049. Epub 2016 Dec 15.
Cell Cycle Remodeling and Zygotic Gene Activation at the Midblastula Transition. Zhang M, Skirkanich J, Lampson MA, Klein PS. Adv Exp Med Biol. 2017;953:441-487. Review.
Systems biology: Molecular memoirs of a cellular family. Beck LE, Raj A. Nature. 2017 Jan 5;541(7635):38-39. doi: 10.1038/nature21101. Epub 2016 Dec 14. No abstract available.
Biochemical and Cellular Determinants of Renal Glomerular Elasticity. Embry AE, Mohammadi H, Niu X, Liu L, Moe B, Miller-Little WA, Lu CY, Bruggeman LA, McCulloch CA, Janmey PA, Miller RT. PLoS One. 2016 Dec 12;11(12):e0167924. doi: 10.1371/journal.pone.0167924. eCollection 2016.
Colloidal Cluster Assembly into Ordered Superstructures via Engineered Directional Binding. Zanjani MB, Jenkins IC, Crocker JC, Sinno T. ACS Nano. 2016 Dec 27;10(12):11280-11289. doi: 10.1021/acsnano.6b06415. Epub 2016 Dec 12.
Matrix rigidity regulates microtubule network polarization in migration. Raab M, Discher DE. Cytoskeleton (Hoboken). 2017 Mar;74(3):114-124. doi: 10.1002/cm.21349. Epub 2017 Jan 31.
Molecular determinants of KA1 domain-mediated autoinhibition and phospholipid activation of MARK1 kinase. Emptage RP, Lemmon MA, Ferguson KM. Biochem J. 2017 Feb 1;474(3):385-398. doi: 10.1042/BCJ20160792. Epub 2016 Nov 22.
Fibrous nonlinear elasticity enables positive mechanical feedback between cells and ECMs. Hall MS, Alisafaei F, Ban E, Feng X, Hui CY, Shenoy VB, Wu M. Proc Natl Acad Sci U S A. 2016 Dec 6;113(49):14043-14048. Epub 2016 Nov 21.
Endotoxemia contributes to CD27+ memory B-cell apoptosis via enhanced sensitivity to Fas ligation in patients with Cirrhosis. Chang LY, Li Y, Kaplan DE. Sci Rep. 2016 Nov 18;6:36862. doi: 10.1038/srep36862.
Prediction of Mortality in Chronic Liver Disease Using Non-hepatic Comorbidities: No SI of Relief as Yet. Kaplan DE. Dig Dis Sci. 2017 Jan;62(1):1-3. doi: 10.1007/s10620-016-4378-9. No abstract available.
Nanoparticle stochastic motion in the inertial regime and hydrodynamic interactions close to a cylindrical wall. Vitoshkin H, Yu HY, Eckmann DM, Ayyaswamy PS, Radhakrishnan R. Phys Rev Fluids. 2016;1. pii: 054104. Epub 2016 Sep 28.
Break-induced telomere synthesis underlies alternative telomere maintenance. Dilley RL, Verma P, Cho NW, Winters HD, Wondisford AR, Greenberg RA. Nature. 2016 Nov 3;539(7627):54-58. doi: 10.1038/nature20099. Epub 2016 Oct 19.
Membrane Shape Instability Induced by Protein Crowding. Chen Z, Atefi E, Baumgart T. Biophys J. 2016 Nov 1;111(9):1823-1826. doi: 10.1016/j.bpj.2016.09.039.
Measuring the Stiffness of Ex Vivo Mouse Aortas Using Atomic Force Microscopy. Bae YH, Liu SL, Byfield FJ, Janmey PA, Assoian RK. J Vis Exp. 2016 Oct 19;(116). doi: 10.3791/54630.
CXCR2-Dependent Accumulation of Tumor-Associated Neutrophils Regulates T-cell Immunity in Pancreatic Ductal Adenocarcinoma. Chao T, Furth EE, Vonderheide RH. Cancer Immunol Res. 2016 Nov;4(11):968-982. Epub 2016 Oct 13.
Nuclear constriction segregates mobile nuclear proteins away from chromatin. Irianto J, Pfeifer CR, Bennett RR, Xia Y, Ivanovska IL, Liu AJ, Greenberg RA, Discher DE. Mol Biol Cell. 2016 Dec 15;27(25):4011-4020. Epub 2016 Oct 26.
Shape changing thin films powered by DNA hybridization. Shim TS, Estephan ZG, Qian Z, Prosser JH, Lee SY, Chenoweth DM, Lee D, Park SJ, Crocker JC. Nat Nanotechnol. 2017 Jan;12(1):41-47. doi: 10.1038/nnano.2016.192. Epub 2016 Oct 24.
The N-Terminal Amphipathic Helix of Endophilin Does Not Contribute to Its Molecular Curvature Generation Capacity. Chen Z, Zhu C, Kuo CJ, Robustelli J, Baumgart T. J Am Chem Soc. 2016 Nov 9;138(44):14616-14622. Epub 2016 Oct 28.
The effect of maternity care coordination services on utilization of postpartum contraceptive services. Rutledge RI, Domino ME, Hillemeier MM, Wells R. Contraception. 2016 Nov;94(5):541-547. doi: 10.1016/j.contraception.2016.06.007. Epub 2016 Jun 24.
Overcoming resistance to HER2 inhibitors through state-specific kinase binding. Novotny CJ, Pollari S, Park JH, Lemmon MA, Shen W, Shokat KM. Nat Chem Biol. 2016 Nov;12(11):923-930. doi: 10.1038/nchembio.2171. Epub 2016 Sep 5.
Fibronectin Extra Domain A Promotes Liver Sinusoid Repair following Hepatectomy. Sackey-Aboagye B, Olsen AL, Mukherjee SM, Ventriglia A, Yokosaki Y, Greenbaum LE, Lee GY, Naga H, Wells RG. PLoS One. 2016 Oct 14;11(10):e0163737. doi: 10.1371/journal.pone.0163737. eCollection 2016.
Esophageal Lichen Planus: Clinical and Radiographic Findings in Eight Patients. Rauschecker AM, Levine MS, Whitson MJ, Tondon R, Rubesin SE, Furth EE, Metz DC. AJR Am J Roentgenol. 2017 Jan;208(1):101-106. doi: 10.2214/AJR.16.16793. Epub 2016 Oct 11.
A Chemomechanical Model for Nuclear Morphology and Stresses during Cell Transendothelial Migration. Cao X, Moeendarbary E, Isermann P, Davidson PM, Wang X, Chen MB, Burkart AK, Lammerding J, Kamm RD, Shenoy VB. Biophys J. 2016 Oct 4;111(7):1541-1552. doi: 10.1016/j.bpj.2016.08.011.
Matrix viscoplasticity and its shielding by active mechanics in microtissue models: experiments and mathematical modeling. Liu AS, Wang H, Copeland CR, Chen CS, Shenoy VB, Reich DH. Sci Rep. 2016 Sep 27;6:33919. doi: 10.1038/srep33919.
Thermodynamic free energy methods to investigate shape transitions in bilayer membranes. Ramakrishnan N, Tourdot RW, Radhakrishnan R. Int J Adv Eng Sci Appl Math. 2016 Jun;8(2):88-100. Epub 2016 Jan 22.
Lipid Head Group Charge and Fatty Acid Configuration Dictate Liposome Mobility in Neurofilament Networks. Arends F, Chaudhary H, Janmey P, Claessens MM, Lieleg O. Macromol Biosci. 2017 Feb;17(2). doi: 10.1002/mabi.201600229. Epub 2016 Sep 12.
Self-Sorting and Coassembly of Fluorinated, Hydrogenated, and Hybrid Janus Dendrimers into Dendrimersomes. Xiao Q, Rubien JD, Wang Z, Reed EH, Hammer DA, Sahoo D, Heiney PA, Yadavalli SS, Goulian M, Wilner SE, Baumgart T, Vinogradov SA, Klein ML, Percec V. J Am Chem Soc. 2016 Sep 28;138(38):12655-63. doi: 10.1021/jacs.6b08069. Epub 2016 Sep 14.
Nuclear lamins in cancer. Irianto J, Pfeifer CR, Ivanovska IL, Swift J, Discher DE. Cell Mol Bioeng. 2016 Jun;9(2):258-267. Epub 2016 Apr 18.
HER3 Expression Is a Marker of Tumor Progression in Premalignant Lesions of the Gastroesophageal Junction. Ecker BL, Taylor L, Zhang PJ, Furth EE, Ginsberg GG, McMillan MT, Datta J, Czerniecki BJ, Roses RE. PLoS One. 2016 Aug 25;11(8):e0161781. doi: 10.1371/journal.pone.0161781. eCollection 2016.
Curvature-undulation coupling as a basis for curvature sensing and generation in bilayer membranes. Bradley RP, Radhakrishnan R. Proc Natl Acad Sci U S A. 2016 Aug 30;113(35):E5117-24. doi: 10.1073/pnas.1605259113. Epub 2016 Aug 16.
Identifying barriers to hepatocellular carcinoma surveillance in a national sample of patients with cirrhosis. Goldberg DS, Taddei TH, Serper M, Mehta R, Dieperink E, Aytaman A, Baytarian M, Fox R, Hunt K, Pedrosa M, Pocha C, Valderrama A, Kaplan DE. Hepatology. 2017 Mar;65(3):864-874. doi: 10.1002/hep.28765. Epub 2016 Oct 5.
The long non-coding RNA Morrbid regulates Bim and short-lived myeloid cell lifespan. Kotzin JJ, Spencer SP, McCright SJ, Kumar DBU, Collet MA, Mowel WK, Elliott EN, Uyar A, Makiya MA, Dunagin MC, Harman CCD, Virtue AT, Zhu S, Bailis W, Stein J, Hughes C, Raj A, Wherry EJ, Goff LA, Klion AD, Rinn JL, Williams A, et al. Nature. 2016 Sep 8;537(7619):239-243. doi: 10.1038/nature19346. Epub 2016 Aug 15.
Scaling ansatz for the jamming transition. Goodrich CP, Liu AJ, Sethna JP. Proc Natl Acad Sci U S A. 2016 Aug 30;113(35):9745-50. doi: 10.1073/pnas.1601858113. Epub 2016 Aug 10.
In vivo imaging of DNA double-strand break induced telomere mobility during alternative lengthening of telomeres. Cho NW, Lampson MA, Greenberg RA. Methods. 2017 Feb 1;114:54-59. doi: 10.1016/j.ymeth.2016.07.010. Epub 2016 Aug 1.
Leishmania major Infection-Induced VEGF-A/VEGFR-2 Signaling Promotes Lymphangiogenesis That Controls Disease. Weinkopff T, Konradt C, Christian DA, Discher DE, Hunter CA, Scott P. J Immunol. 2016 Sep 1;197(5):1823-31. doi: 10.4049/jimmunol.1600717. Epub 2016 Jul 29.
Deciphering the Duality of Clock and Growth Metabolism in a Cell Autonomous System Using NMR Profiling of the Secretome. Sengupta A, Krishnaiah SY, Rhoades S, Growe J, Slaff B, Venkataraman A, Olarerin-George AO, Van Dang C, Hogenesch JB, Weljie AM. Metabolites. 2016 Jul 27;6(3). pii: E23. doi: 10.3390/metabo6030023.
Transcriptional Bursting Explains the Noise-Versus-Mean Relationship in mRNA and Protein Levels. Dar RD, Shaffer SM, Singh A, Razooky BS, Simpson ML, Raj A, Weinberger LS. PLoS One. 2016 Jul 28;11(7):e0158298. doi: 10.1371/journal.pone.0158298. eCollection 2016.
Mechanical signaling coordinates the embryonic heartbeat. Chiou KK, Rocks JW, Chen CY, Cho S, Merkus KE, Rajaratnam A, Robison P, Tewari M, Vogel K, Majkut SF, Prosser BL, Discher DE, Liu AJ. Proc Natl Acad Sci U S A. 2016 Aug 9;113(32):8939-44. doi: 10.1073/pnas.1520428113. Epub 2016 Jul 25.
Diagnostic accuracy of hepatorenal index in the detection and grading of hepatic steatosis. Chauhan A, Sultan LR, Furth EE, Jones LP, Khungar V, Sehgal CM. J Clin Ultrasound. 2016 Nov 12;44(9):580-586. doi: 10.1002/jcu.22382. Epub 2016 Jul 22.
DNA Island Formation on Binary Block Copolymer Vesicles. Luo Q, Shi Z, Zhang Y, Chen XJ, Han SY, Baumgart T, Chenoweth DM, Park SJ. J Am Chem Soc. 2016 Aug 17;138(32):10157-62. doi: 10.1021/jacs.6b04076. Epub 2016 Aug 3.
Biophysically inspired model for functionalized nanocarrier adhesion to cell surface: roles of protein expression and mechanical factors. Ramakrishnan N, Tourdot RW, Eckmann DM, Ayyaswamy PS, Muzykantov VR, Radhakrishnan R. R Soc Open Sci. 2016 Jun 29;3(6):160260. doi: 10.1098/rsos.160260. eCollection 2016 Jun.
Nanoscale imaging of RNA with expansion microscopy. Chen F, Wassie AT, Cote AJ, Sinha A, Alon S, Asano S, Daugharthy ER, Chang JB, Marblestone A, Church GM, Raj A, Boyden ES. Nat Methods. 2016 Aug;13(8):679-84. doi: 10.1038/nmeth.3899. Epub 2016 Jul 4.
Choreographing the Double Strand Break Response: Ubiquitin and SUMO Control of Nuclear Architecture. Harding SM, Greenberg RA. Front Genet. 2016 Jun 7;7:103. doi: 10.3389/fgene.2016.00103. eCollection 2016. Review.
Pinning Susceptibility: The Effect of Dilute, Quenched Disorder on Jamming. Graves AL, Nashed S, Padgett E, Goodrich CP, Liu AJ, Sethna JP. Phys Rev Lett. 2016 Jun 10;116(23):235501. doi: 10.1103/PhysRevLett.116.235501. Epub 2016 Jun 10.
A hyperactive transcriptional state marks genome reactivation at the mitosis-G1 transition. Hsiung CC, Bartman CR, Huang P, Ginart P, Stonestrom AJ, Keller CA, Face C, Jahn KS, Evans P, Sankaranarayanan L, Giardine B, Hardison RC, Raj A, Blobel GA. Genes Dev. 2016 Jun 15;30(12):1423-39. doi: 10.1101/gad.280859.116.
Understanding soft glassy materials using an energy landscape approach. Hwang HJ, Riggleman RA, Crocker JC. Nat Mater. 2016 Sep;15(9):1031-6. doi: 10.1038/nmat4663. Epub 2016 Jun 20.
SnapShot: Mechanosensing Matrix. Irianto J, Pfeifer CR, Xia Y, Discher DE. Cell. 2016 Jun 16;165(7):1820-1820.e1. doi: 10.1016/j.cell.2016.06.002.
The role of electronic coupling between substrate and 2D MoS2 nanosheets in electrocatalytic production of hydrogen. Voiry D, Fullon R, Yang J, de Carvalho Castro E Silva C, Kappera R, Bozkurt I, Kaplan D, Lagos MJ, Batson PE, Gupta G, Mohite AD, Dong L, Er D, Shenoy VB, Asefa T, Chhowalla M. Nat Mater. 2016 Sep;15(9):1003-9. doi: 10.1038/nmat4660. Epub 2016 Jun 13.
A Radiotracer Strategy to Quantify PARP-1 Expression In Vivo Provides a Biomarker That Can Enable Patient Selection for PARP Inhibitor Therapy. Makvandi M, Xu K, Lieberman BP, Anderson RC, Effron SS, Winters HD, Zeng C, McDonald ES, Pryma DA, Greenberg RA, Mach RH. Cancer Res. 2016 Aug 1;76(15):4516-24. doi: 10.1158/0008-5472.CAN-16-0416. Epub 2016 Jun 3.
What’s Luck Got to Do with It: Single Cells, Multiple Fates, and Biological Nondeterminism. Symmons O, Raj A. Mol Cell. 2016 Jun 2;62(5):788-802. doi: 10.1016/j.molcel.2016.05.023. Review.
Efficacy of Sofosbuvir Plus Ribavirin in Veterans With Hepatitis C Virus Genotype 2 Infection, Compensated Cirrhosis, and Multiple Comorbidities. Ho SB, Monto A, Peyton A, Kaplan DE, Byrne S, Moon S, Copans A, Rossaro L, Roy A, Le H, Dvory-Sobol H, Zhu Y, Brainard DM, Guyer W, Shaikh O, Fuchs M, Morgan TR; VALOR study team.. Clin Gastroenterol Hepatol. 2017 Feb;15(2):282-288. doi: 10.1016/j.cgh.2016.05.024. Epub 2016 May 27.
Cholesterol-Dependent Phase-Demixing in Lipid Bilayers as a Switch for the Activity of the Phosphoinositide-Binding Cytoskeletal Protein Gelsolin. Wang YH, Bucki R, Janmey PA. Biochemistry. 2016 Jun 21;55(24):3361-9. doi: 10.1021/acs.biochem.5b01363. Epub 2016 Jun 9.
Noncanonical views of homology-directed DNA repair. Verma P, Greenberg RA. Genes Dev. 2016 May 15;30(10):1138-54. doi: 10.1101/gad.280545.116. Review.
Synthesis of two-dimensional titanium nitride Ti4N3 (MXene). Urbankowski P, Anasori B, Makaryan T, Er D, Kota S, Walsh PL, Zhao M, Shenoy VB, Barsoum MW, Gogotsi Y. Nanoscale. 2016 Jun 2;8(22):11385-91. doi: 10.1039/c6nr02253g.
Clinicopathogenomic analysis of mismatch repair proficient colorectal adenocarcinoma uncovers novel prognostic subgroups with differing patterns of genetic evolution. Braxton DR, Zhang R, Morrissette JD, Loaiza-Bonilla A, Furth EE. Int J Cancer. 2016 Oct 1;139(7):1546-56. doi: 10.1002/ijc.30196. Epub 2016 Jun 1.
Probing Mitosis by Manipulating the Interactions of Mitotic Regulator Proteins Using Rapamycin-Inducible Dimerization. Ballister ER, Lampson MA. Methods Mol Biol. 2016;1413:325-31. doi: 10.1007/978-1-4939-3542-0_20.
Filomicelles from aromatic diblock copolymers increase paclitaxel-induced tumor cell death and aneuploidy compared with aliphatic copolymers. Nair PR, Karthick SA, Spinler KR, Vakili MR, Lavasanifar A, Discher DE. Nanomedicine (Lond). 2016 Jun;11(12):1551-69. doi: 10.2217/nnm-2016-0007. Epub 2016 May 13.
Gradually softening hydrogels for modeling hepatic stellate cell behavior during fibrosis regression. Caliari SR, Perepelyuk M, Soulas EM, Lee GY, Wells RG, Burdick JA. Integr Biol (Camb). 2016 Jun 13;8(6):720-8. doi: 10.1039/c6ib00027d. Epub 2016 May 10.
Glutathione antioxidant pathway activity and reserve determine toxicity and specificity of the biliary toxin biliatresone in zebrafish. Zhao X, Lorent K, Wilkins BJ, Marchione DM, Gillespie K, Waisbourd-Zinman O, So J, Koo KA, Shin D, Porter JR, Wells RG, Blair I, Pack M. Hepatology. 2016 Sep;64(3):894-907. doi: 10.1002/hep.28603. Epub 2016 Jun 11.
Detyrosinated microtubules buckle and bear load in contracting cardiomyocytes. Robison P, Caporizzo MA, Ahmadzadeh H, Bogush AI, Chen CY, Margulies KB, Shenoy VB, Prosser BL. Science. 2016 Apr 22;352(6284):aaf0659. doi: 10.1126/science.aaf0659.
Structural Properties of Defects in Glassy Liquids. Cubuk ED, Schoenholz SS, Kaxiras E, Liu AJ. J Phys Chem B. 2016 Jul 7;120(26):6139-46. doi: 10.1021/acs.jpcb.6b02144. Epub 2016 May 2.
The toxin biliatresone causes mouse extrahepatic cholangiocyte damage and fibrosis through decreased glutathione and SOX17. Waisbourd-Zinman O, Koh H, Tsai S, Lavrut PM, Dang C, Zhao X, Pack M, Cave J, Hawes M, Koo KA, Porter JR, Wells RG. Hepatology. 2016 Sep;64(3):880-93. doi: 10.1002/hep.28599. Epub 2016 May 20.
Deletion Mutations Keep Kinase Inhibitors in the Loop. Freed DM, Park JH, Radhakrishnan R, Lemmon MA. Cancer Cell. 2016 Apr 11;29(4):423-425. doi: 10.1016/j.ccell.2016.03.017.
[(18)F]FluorThanatrace uptake as a marker of PARP1 expression and activity in breast cancer. Edmonds CE, Makvandi M, Lieberman BP, Xu K, Zeng C, Li S, Hou C, Lee H, Greenberg RA, Mankoff DA, Mach RH. Am J Nucl Med Mol Imaging. 2016 Jan 28;6(1):94-101. eCollection 2016.
Enhancer Regulation of Transcriptional Bursting Parameters Revealed by Forced Chromatin Looping. Bartman CR, Hsu SC, Hsiung CC, Raj A, Blobel GA. Mol Cell. 2016 Apr 21;62(2):237-47. doi: 10.1016/j.molcel.2016.03.007. Epub 2016 Apr 7.
Improved Survival Among all Interferon-α-Treated Patients in HCV-002, a Veterans Affairs Hepatitis C Cohort of 2211 Patients, Despite Increased Cirrhosis Among Nonresponders. Cozen ML, Ryan JC, Shen H, Cheung R, Kaplan DE, Pocha C, Brau N, Aytaman A, Schmidt WN, Pedrosa M, Anand BS, Chang KM, Morgan T, Monto A. Dig Dis Sci. 2016 Jun;61(6):1744-56. doi: 10.1007/s10620-016-4122-5. Epub 2016 Apr 8.
Long-Term Retention of CENP-A Nucleosomes in Mammalian Oocytes Underpins Transgenerational Inheritance of Centromere Identity. Smoak EM, Stein P, Schultz RM, Lampson MA, Black BE. Curr Biol. 2016 Apr 25;26(8):1110-6. doi: 10.1016/j.cub.2016.02.061. Epub 2016 Mar 31.
KDR Mutation as a Novel Predictive Biomarker of Exceptional Response to Regorafenib in Metastatic Colorectal Cancer. Loaiza-Bonilla A, Jensen CE, Shroff S, Furth E, Bonilla-Reyes PA, Deik AF, Morrissette J. Cureus. 2016 Feb 3;8(2):e478. doi: 10.7759/cureus.478.
Spatial structure of states of self stress in jammed systems. Sussman DM, Goodrich CP, Liu AJ. Soft Matter. 2016 May 7;12(17):3982-90. doi: 10.1039/c6sm00094k. Epub 2016 Mar 21.
Two-Dimensional π-Conjugated Covalent-Organic Frameworks as Quantum Anomalous Hall Topological Insulators. Dong L, Kim Y, Er D, Rappe AM, Shenoy VB. Phys Rev Lett. 2016 Mar 4;116(9):096601. doi: 10.1103/PhysRevLett.116.096601. Epub 2016 Feb 29.
Divergence of Voronoi Cell Anisotropy Vector: A Threshold-Free Characterization of Local Structure in Amorphous Materials. Rieser JM, Goodrich CP, Liu AJ, Durian DJ. Phys Rev Lett. 2016 Feb 26;116(8):088001. doi: 10.1103/PhysRevLett.116.088001. Epub 2016 Feb 23.
Visualizing allele-specific expression in single cells reveals epigenetic mosaicism in an H19 loss-of-imprinting mutant. Ginart P, Kalish JM, Jiang CL, Yu AC, Bartolomei MS, Raj A. Genes Dev. 2016 Mar 1;30(5):567-78. doi: 10.1101/gad.275958.115.
Single-cell differences in matrix gene expression do not predict matrix deposition. Cote AJ, McLeod CM, Farrell MJ, McClanahan PD, Dunagin MC, Raj A, Mauck RL. Nat Commun. 2016 Mar 3;7:10865. doi: 10.1038/ncomms10865.
Overlapping cell population expression profiling and regulatory inference in C. elegans. Burdick J, Walton T, Preston E, Zacharias A, Raj A, Murray JI. BMC Genomics. 2016 Feb 29;17:159. doi: 10.1186/s12864-016-2482-z.
Location, location, location: Cell-level mechanics in liver fibrosis. Wells RG. Hepatology. 2016 Jul;64(1):32-3. doi: 10.1002/hep.28519. Epub 2016 Apr 4. No abstract available.
Stiffening hydrogels for investigating the dynamics of hepatic stellate cell mechanotransduction during myofibroblast activation. Caliari SR, Perepelyuk M, Cosgrove BD, Tsai SJ, Lee GY, Mauck RL, Wells RG, Burdick JA. Sci Rep. 2016 Feb 24;6:21387. doi: 10.1038/srep21387.
Limits of Coherency and Strain Transfer in Flexible 2D van der Waals Heterostructures: Formation of Strain Solitons and Interlayer Debonding. Kumar H, Dong L, Shenoy VB. Sci Rep. 2016 Feb 12;6:21516. doi: 10.1038/srep21516.
A chemo-mechanical free-energy-based approach to model durotaxis and extracellular stiffness-dependent contraction and polarization of cells. Shenoy VB, Wang H, Wang X. Interface Focus. 2016 Feb 6;6(1):20150067. doi: 10.1098/rsfs.2015.0067.
Freewheeling sisters cause problems. Akera T, Lampson MA. Elife. 2016 Feb 2;5:e13788. doi: 10.7554/eLife.13788.
Methods for Determining the Cellular Functions of Vimentin Intermediate Filaments. Ridge KM, Shumaker D, Robert A, Hookway C, Gelfand VI, Janmey PA, Lowery J, Guo M, Weitz DA, Kuczmarski E, Goldman RD. Methods Enzymol. 2016;568:389-426. doi: 10.1016/bs.mie.2015.09.036. Epub 2015 Dec 19.
Mechanical Properties of Intermediate Filament Proteins. Charrier EE, Janmey PA. Methods Enzymol. 2016;568:35-57. doi: 10.1016/bs.mie.2015.09.009. Epub 2015 Nov 3.
Bistability of a coupled Aurora B kinase-phosphatase system in cell division. Zaytsev AV, Segura-Peña D, Godzi M, Calderon A, Ballister ER, Stamatov R, Mayo AM, Peterson L, Black BE, Ataullakhanov FI, Lampson MA, Grishchuk EL. Elife. 2016 Jan 14;5:e10644. doi: 10.7554/eLife.10644.
Uncoupling shear and uniaxial elastic moduli of semiflexible biopolymer networks: compression-softening and stretch-stiffening. van Oosten AS, Vahabi M, Licup AJ, Sharma A, Galie PA, MacKintosh FC, Janmey PA. Sci Rep. 2016 Jan 13;6:19270. doi: 10.1038/srep19270.
Spontaneous Pancreatitis Caused by Tissue-Specific Gene Ablation of Hhex in Mice. Ferreira MJ, McKenna LB, Zhang J, Reichert M, Bakir B, Buza EL, Furth EE, Bogue CW, Rustgi AK, Kaestner KH. Cell Mol Gastroenterol Hepatol. 2015 Sep 1;1(5):550-569. doi: 10.1016/j.jcmgh.2015.06.007.
Normal and Fibrotic Rat Livers Demonstrate Shear Strain Softening and Compression Stiffening: A Model for Soft Tissue Mechanics. Perepelyuk M, Chin L, Cao X, van Oosten A, Shenoy VB, Janmey PA, Wells RG. PLoS One. 2016 Jan 6;11(1):e0146588. doi: 10.1371/journal.pone.0146588. eCollection 2016.
Eosinophilic Esophagitis-Associated Chemical and Mechanical Microenvironment Shapes Esophageal Fibroblast Behavior. Muir AB, Dods K, Henry SJ, Benitez AJ, Lee D, Whelan KA, DeMarshall M, Hammer DA, Falk G, Wells RG, Spergel J, Nakagawa H, Wang ML. J Pediatr Gastroenterol Nutr. 2016 Aug;63(2):200-9. doi: 10.1097/MPG.0000000000001100.
Reactivity of Biliatresone, a Natural Biliary Toxin, with Glutathione, Histamine, and Amino Acids. Koo KA, Waisbourd-Zinman O, Wells RG, Pack M, Porter JR. Chem Res Toxicol. 2016 Feb 15;29(2):142-9. doi: 10.1021/acs.chemrestox.5b00308. Epub 2016 Jan 13.
Salmon-derived thrombin inhibits development of chronic pain through an endothelial barrier protective mechanism dependent on APC. Smith JR, Galie PA, Slochower DR, Weisshaar CL, Janmey PA, Winkelstein BA. Biomaterials. 2016 Feb;80:96-105. doi: 10.1016/j.biomaterials.2015.11.062. Epub 2015 Dec 2.
CD14(+) regulatory dendritic cells in patients with hepatocellular carcinoma and cirrhosis. Tanoue S, Kaplan DE. Hepatology. 2016 Apr;63(4):1391-2. doi: 10.1002/hep.28419. Epub 2016 Feb 19. No abstract available.
ALTernative Telomere Maintenance and Cancer. Dilley RL, Greenberg RA. Trends Cancer. 2015 Oct 1;1(2):145-156.
Evidence and Model for Strain-Driven Release of Metal Nanocatalysts from Perovskites during Exsolution. Oh TS, Rahani EK, Neagu D, Irvine JT, Shenoy VB, Gorte RJ, Vohs JM. J Phys Chem Lett. 2015 Dec 17;6(24):5106-10. doi: 10.1021/acs.jpclett.5b02292. Epub 2015 Dec 9.
Recruitment of Pontin/Reptin by E2f1 amplifies E2f transcriptional response during cancer progression. Tarangelo A, Lo N, Teng R, Kim E, Le L, Watson D, Furth EE, Raman P, Ehmer U, Viatour P. Nat Commun. 2015 Dec 7;6:10028. doi: 10.1038/ncomms10028.
Mechanical Effects of Dynamic Binding between Tau Proteins on Microtubules during Axonal Injury. Ahmadzadeh H, Smith DH, Shenoy VB. Biophys J. 2015 Dec 1;109(11):2328-37. doi: 10.1016/j.bpj.2015.09.010.
Harnessing cellular-derived forces in self-assembled microtissues to control the synthesis and alignment of ECM. Schell JY, Wilks BT, Patel M, Franck C, Chalivendra V, Cao X, Shenoy VB, Morgan JR. Biomaterials. 2016 Jan;77:120-9. doi: 10.1016/j.biomaterials.2015.10.080. Epub 2015 Nov 2.
Immunopathogenesis of Hepatitis C Virus Infection. Kaplan DE. Gastroenterol Clin North Am. 2015 Dec;44(4):735-60. doi: 10.1016/j.gtc.2015.07.004. Epub 2015 Aug 13. Review.
Application of a free-energy-landscape approach to study tension-dependent bilayer tubulation mediated by curvature-inducing proteins. Tourdot RW, Ramakrishnan N, Baumgart T, Radhakrishnan R. Phys Rev E Stat Nonlin Soft Matter Phys. 2015 Oct;92(4):042715. doi: 10.1103/PhysRevE.92.042715. Epub 2015 Oct 29. Erratum in: Phys Rev E. 2016 May;93(5-2):059902.
Care delivery and outcomes among US veterans with hepatitis B: A national cohort study. Serper M, Choi G, Forde KA, Kaplan DE. Hepatology. 2016 Jun;63(6):1774-82. doi: 10.1002/hep.28340. Epub 2016 Feb 25.
The ALK/ROS1 Inhibitor PF-06463922 Overcomes Primary Resistance to Crizotinib in ALK-Driven Neuroblastoma. Infarinato NR, Park JH, Krytska K, Ryles HT, Sano R, Szigety KM, Li Y, Zou HY, Lee NV, Smeal T, Lemmon MA, Mossé YP. Cancer Discov. 2016 Jan;6(1):96-107. doi: 10.1158/2159-8290.CD-15-1056. Epub 2015 Nov 10.
A Chemomechanical Model of Matrix and Nuclear Rigidity Regulation of Focal Adhesion Size. Cao X, Lin Y, Driscoll TP, Franco-Barraza J, Cukierman E, Mauck RL, Shenoy VB. Biophys J. 2015 Nov 3;109(9):1807-17. doi: 10.1016/j.bpj.2015.08.048.
Unexpected TTF-1 Positivity in a Subset of Gastric Adenocarcinomas. Choi SM, Furth EE, Zhang PJ. Appl Immunohistochem Mol Morphol. 2016 Sep;24(8):603-7. doi: 10.1097/PAI.0000000000000244.
Cell-mediated fibre recruitment drives extracellular matrix mechanosensing in engineered fibrillar microenvironments. Baker BM, Trappmann B, Wang WY, Sakar MS, Kim IL, Shenoy VB, Burdick JA, Chen CS. Nat Mater. 2015 Dec;14(12):1262-8. doi: 10.1038/nmat4444. Epub 2015 Oct 12.
The reason sickle reticulocytes expose PS. Discher DE, Ney PA. Blood. 2015 Oct 8;126(15):1737-8. doi: 10.1182/blood-2015-08-665117.
Dynamic enhancer-gene body contacts during transcription elongation. Lee K, Hsiung CC, Huang P, Raj A, Blobel GA. Genes Dev. 2015 Oct 1;29(19):1992-7. doi: 10.1101/gad.255265.114. Erratum in: Genes Dev. 2015 Oct 15;29(20):2217.
Identification of a Natural Viral RNA Motif That Optimizes Sensing of Viral RNA by RIG-I. Xu J, Mercado-López X, Grier JT, Kim WK, Chun LF, Irvine EB, Del Toro Duany Y, Kell A, Hur S, Gale M Jr, Raj A, López CB. MBio. 2015 Oct 6;6(5):e01265-15. doi: 10.1128/mBio.01265-15.
ATM Dependent Silencing Links Nucleolar Chromatin Reorganization to DNA Damage Recognition. Harding SM, Boiarsky JA, Greenberg RA. Cell Rep. 2015 Oct 13;13(2):251-9. doi: 10.1016/j.celrep.2015.08.085. Epub 2015 Oct 1.
Crystal-Templated Colloidal Clusters Exhibit Directional DNA Interactions. McGinley JT, Wang Y, Jenkins IC, Sinno T, Crocker JC. ACS Nano. 2015 Nov 24;9(11):10817-25. doi: 10.1021/acsnano.5b03272. Epub 2015 Oct 12.
EGFR mutations cause a lethal syndrome of epithelial dysfunction with progeroid features. Ganetzky R, Finn E, Bagchi A, Zollo O, Conlin L, Deardorff M, Harr M, Simpson MA, McGrath JA, Zackai E, Lemmon MA, Sondheimer N. Mol Genet Genomic Med. 2015 Sep;3(5):452-8. doi: 10.1002/mgg3.156. Epub 2015 Jun 4.
Half dozen of one, six billion of the other: What can small- and large-scale molecular systems biology learn from one another? Mellis IA, Raj A. Genome Res. 2015 Oct;25(10):1466-72. doi: 10.1101/gr.190579.115.
Beyond the Impact Factor: Why CMGH? Wells RG. Cell Mol Gastroenterol Hepatol. 2015 Oct 1;1(6):571. doi: 10.1016/j.jcmgh.2015.09.006. eCollection 2015 Nov. No abstract available.
Minimal model for collective kinetochore-microtubule dynamics. Banigan EJ, Chiou KK, Ballister ER, Mayo AM, Lampson MA, Liu AJ. Proc Natl Acad Sci U S A. 2015 Oct 13;112(41):12699-704. doi: 10.1073/pnas.1513512112. Epub 2015 Sep 28. Erratum in: Proc Natl Acad Sci U S A. 2016 Oct 18;113(42):E6546.
Strain fluctuations and elastic moduli in disordered solids. Sussman DM, Schoenholz SS, Xu Y, Still T, Yodh AG, Liu AJ. Phys Rev E Stat Nonlin Soft Matter Phys. 2015 Aug;92(2):022307. Epub 2015 Aug 20.
Accelerated reproductive aging in females lacking a novel centromere protein SYCP2L. Zhou J, Stein P, Leu NA, Chmátal L, Xue J, Ma J, Huang X, Lampson MA, Schultz RM, Wang PJ. Hum Mol Genet. 2015 Nov 15;24(22):6505-14. doi: 10.1093/hmg/ddv359. Epub 2015 Sep 11.
A comparison of hyperelastic constitutive models applicable to brain and fat tissues. Mihai LA, Chin L, Janmey PA, Goriely A. J R Soc Interface. 2015 Sep 6;12(110):0486. doi: 10.1098/rsif.2015.0486.
Higher-Order Assembly of BRCC36-KIAA0157 Is Required for DUB Activity and Biological Function. Zeqiraj E, Tian L, Piggott CA, Pillon MC, Duffy NM, Ceccarelli DF, Keszei AF, Lorenzen K, Kurinov I, Orlicky S, Gish GD, Heck AJ, Guarné A, Greenberg RA, Sicheri F. Mol Cell. 2015 Sep 17;59(6):970-83. doi: 10.1016/j.molcel.2015.07.028. Epub 2015 Sep 3.
MERIT40 cooperates with BRCA2 to resolve DNA interstrand cross-links. Jiang Q, Paramasivam M, Aressy B, Wu J, Bellani M, Tong W, Seidman MM, Greenberg RA. Genes Dev. 2015 Sep 15;29(18):1955-68. doi: 10.1101/gad.264192.115. Epub 2015 Sep 3.
Heterogeneous lineage marker expression in naive embryonic stem cells is mostly due to spontaneous differentiation. Nair G, Abranches E, Guedes AM, Henrique D, Raj A. Sci Rep. 2015 Aug 21;5:13339. doi: 10.1038/srep13339.
Protrusive and Contractile Forces of Spreading Human Neutrophils. Henry SJ, Chen CS, Crocker JC, Hammer DA. Biophys J. 2015 Aug 18;109(4):699-709. doi: 10.1016/j.bpj.2015.05.041.
Longitudinal analysis of Plasmodium sporozoite motility in the dermis reveals component of blood vessel recognition. Hopp CS, Chiou K, Ragheb DR, Salman AM, Khan SM, Liu AJ, Sinnis P. Elife. 2015 Aug 13;4. doi: 10.7554/eLife.07789.
Bactericidal Activity of Ceragenin CSA-13 in Cell Culture and in an Animal Model of Peritoneal Infection. Bucki R, Niemirowicz K, Wnorowska U, Byfield FJ, Piktel E, WÄ…tek M, Janmey PA, Savage PB. Antimicrob Agents Chemother. 2015 Oct;59(10):6274-82. doi: 10.1128/AAC.00653-15. Epub 2015 Jul 27.
Interaction potentials from arbitrary multi-particle trajectory data. Jenkins IC, Crocker JC, Sinno T. Soft Matter. 2015 Sep 21;11(35):6948-56. doi: 10.1039/c5sm01233c. Epub 2015 Aug 3.
Motile Human Neutrophils Sense Ligand Density Over Their Entire Contact Area. Henry SJ, Crocker JC, Hammer DA. Ann Biomed Eng. 2016 Apr;44(4):886-94. doi: 10.1007/s10439-015-1408-2. Epub 2015 Jul 29.
Regulation of membrane-shape transitions induced by I-BAR domains. Chen Z, Shi Z, Baumgart T. Biophys J. 2015 Jul 21;109(2):298-307. doi: 10.1016/j.bpj.2015.06.010.
The Principle of Independent Bond-Level Response: Tuning by Pruning to Exploit Disorder for Global Behavior. Goodrich CP, Liu AJ, Nagel SR. Phys Rev Lett. 2015 Jun 5;114(22):225501. Epub 2015 Jun 4.
Development and Performance of an Algorithm to Estimate the Child-Turcotte-Pugh Score From a National Electronic Healthcare Database. Kaplan DE, Dai F, Aytaman A, Baytarian M, Fox R, Hunt K, Knott A, Pedrosa M, Pocha C, Mehta R, Duggal M, Skanderson M, Valderrama A, Taddei TH; VOCAL Study Group.. Clin Gastroenterol Hepatol. 2015 Dec;13(13):2333-41.e1-6. doi: 10.1016/j.cgh.2015.07.010. Epub 2015 Jul 15.
Biliatresone, a Reactive Natural Toxin from Dysphania glomulifera and D. littoralis: Discovery of the Toxic Moiety 1,2-Diaryl-2-Propenone. Koo KA, Lorent K, Gong W, Windsor P, Whittaker SJ, Pack M, Wells RG, Porter JR. Chem Res Toxicol. 2015 Aug 17;28(8):1519-21. doi: 10.1021/acs.chemrestox.5b00227. Epub 2015 Jul 20.
Deformation-driven diffusion and plastic flow in amorphous granular pillars. Li W, Rieser JM, Liu AJ, Durian DJ, Li J. Phys Rev E Stat Nonlin Soft Matter Phys. 2015 Jun;91(6):062212. Epub 2015 Jun 24.
Macrophage engulfment of a cell or nanoparticle is regulated by unavoidable opsonization, a species-specific ‘Marker of Self’ CD47, and target physical properties. Sosale NG, Spinler KR, Alvey C, Discher DE. Curr Opin Immunol. 2015 Aug;35:107-12. doi: 10.1016/j.coi.2015.06.013. Epub 2015 Jul 13. Review.
Fractal heterogeneity in minimal matrix models of scars modulates stiff-niche stem-cell responses via nuclear exit of a mechanorepressor. Dingal PC, Bradshaw AM, Cho S, Raab M, Buxboim A, Swift J, Discher DE. Nat Mater. 2015 Sep;14(9):951-60. doi: 10.1038/nmat4350. Epub 2015 Jul 13.
Spatial Regulation of Kinetochore Microtubule Attachments by Destabilization at Spindle Poles in Meiosis I. Chmátal L, Yang K, Schultz RM, Lampson MA. Curr Biol. 2015 Jul 20;25(14):1835-41. doi: 10.1016/j.cub.2015.05.013. Epub 2015 Jul 9.
Robust hematopoietic progenitor cell commitment in the presence of a conflicting cue. Shah NA, Levesque MJ, Raj A, Sarkar CA. J Cell Sci. 2015 Aug 15;128(16):3009-17. doi: 10.1242/jcs.158436. Epub 2015 Jul 9. Erratum in: J Cell Sci. 2015 Nov 1;128(21):4024.
Recurrence and Survival After Resection of Small Intraductal Papillary Mucinous Neoplasm-associated Carcinomas (≤20-mm Invasive Component): A Multi-institutional Analysis. Winter JM, Jiang W, Basturk O, Mino-Kenudson M, Fong ZV, Tan WP, Lavu H, Vollmer CM, Furth EE, Haviland D, Klimstra DS, Jarnagin WR, Lillemoe KD, Yeo CJ, Fernandez-Del Castillo C, Allen PJ. Ann Surg. 2016 Apr;263(4):793-801. doi: 10.1097/SLA.0000000000001319.
Filamin A Mediates Wound Closure by Promoting Elastic Deformation and Maintenance of Tension in the Collagen Matrix. Mohammadi H, Pinto VI, Wang Y, Hinz B, Janmey PA, McCulloch CA. J Invest Dermatol. 2015 Nov;135(11):2852-2861. doi: 10.1038/jid.2015.251. Epub 2015 Jul 2.
Hydrodynamic interactions of deformable polymeric nanocarriers and the effect of crosslinking. Sarkar A, Eckmann DM, Ayyaswamy PS, Radhakrishnan R. Soft Matter. 2015 Aug 7;11(29):5955-69. doi: 10.1039/c5sm00669d.
Multiplexed detection of viral infections using rapid in situ RNA analysis on a chip. Shaffer SM, Joshi RP, Chambers BS, Sterken D, Biaesch AG, Gabrieli DJ, Li Y, Feemster KA, Hensley SE, Issadore D, Raj A. Lab Chip. 2015 Aug 7;15(15):3170-82. doi: 10.1039/c5lc00459d.
Elastic Deformations in 2D van der waals Heterostructures and their Impact on Optoelectronic Properties: Predictions from a Multiscale Computational Approach. Kumar H, Er D, Dong L, Li J, Shenoy VB. Sci Rep. 2015 Jun 16;5:10872. doi: 10.1038/srep10872.
Composite generalized Langevin equation for Brownian motion in different hydrodynamic and adhesion regimes. Yu HY, Eckmann DM, Ayyaswamy PS, Radhakrishnan R. Phys Rev E Stat Nonlin Soft Matter Phys. 2015 May;91(5):052303. Epub 2015 May 12.
Role played by Prx1-dependent extracellular matrix properties in vascular smooth muscle development in embryonic lungs. Ihida-Stansbury K, Ames J, Chokshi M, Aiad N, Sanyal S, Kawabata KC, Levental I, Sundararaghavan HG, Burdick JA, Janmey P, Miyazono K, Wells RG, Jones PL. Pulm Circ. 2015 Jun;5(2):382-97. doi: 10.1086/681272.
Ligand regulation of a constitutively dimeric EGF receptor. Freed DM, Alvarado D, Lemmon MA. Nat Commun. 2015 Jun 10;6:7380. doi: 10.1038/ncomms8380.
Relationship of and cross-talk between physical and biologic properties of the glomerulus. Miller RT, Janmey PA. Curr Opin Nephrol Hypertens. 2015 Jul;24(4):393-400. doi: 10.1097/MNH.0000000000000138. Review.
Deciphering the BRCA1 Tumor Suppressor Network. Jiang Q, Greenberg RA. J Biol Chem. 2015 Jul 17;290(29):17724-32. doi: 10.1074/jbc.R115.667931. Epub 2015 Jun 5. Review.
Polyelectrolyte-mediated increase of biofilm mass formation. Bucki R, Niemirowicz K, Wnorowska U, Wątek M, Byfield FJ, Cruz K, Wróblewska M, Janmey PA. BMC Microbiol. 2015 Jun 6;15:117. doi: 10.1186/s12866-015-0457-x.
Stem cell mechanobiology: diverse lessons from bone marrow. Ivanovska IL, Shin JW, Swift J, Discher DE. Trends Cell Biol. 2015 Sep;25(9):523-32. doi: 10.1016/j.tcb.2015.04.003. Epub 2015 Jun 2. Review.
Origin and function of myofibroblasts in the liver. Wells RG, Schwabe RF. Semin Liver Dis. 2015 May;35(2):e1. doi: 10.1055/s-0035-1554915. Epub 2015 May 23. No abstract available.
Synthesis and structure-activity relationships of novel cationic lipids with anti-inflammatory and antimicrobial activities. Myint M, Bucki R, Janmey PA, Diamond SL. Bioorg Med Chem Lett. 2015 Jul 15;25(14):2837-43. doi: 10.1016/j.bmcl.2015.04.104. Epub 2015 May 11.
Optogenetic control of organelle transport using a photocaged chemical inducer of dimerization. Ballister ER, Ayloo S, Chenoweth DM, Lampson MA, Holzbaur ELF. Curr Biol. 2015 May 18;25(10):R407-R408. doi: 10.1016/j.cub.2015.03.056. No abstract available.
Origin and function of myofibroblasts in the liver. Wells RG, Schwabe RF. Semin Liver Dis. 2015 May;35(2):97-106. doi: 10.1055/s-0035-1550061. Epub 2015 May 14. Review. Erratum in: Semin Liver Dis. 2015 May;35(2):e1. Schwabe, Robert [corrected to Schwabe, Robert F].
CD317 is over-expressed in B-cell chronic lymphocytic leukemia, but not B-cell acute lymphoblastic leukemia. Gong S, Osei ES, Kaplan D, Chen YH, Meyerson H. Int J Clin Exp Pathol. 2015 Feb 1;8(2):1613-21. eCollection 2015.
Delta hepatitis within the Veterans Affairs medical system in the United States: Prevalence, risk factors, and outcomes. Kushner T, Serper M, Kaplan DE. J Hepatol. 2015 Sep;63(3):586-92. doi: 10.1016/j.jhep.2015.04.025. Epub 2015 May 8.
Chromosomes. CENP-C reshapes and stabilizes CENP-A nucleosomes at the centromere. Falk SJ, Guo LY, Sekulic N, Smoak EM, Mani T, Logsdon GA, Gupta K, Jansen LE, Van Duyne GD, Vinogradov SA, Lampson MA, Black BE. Science. 2015 May 8;348(6235):699-703. doi: 10.1126/science.1259308.
Identification of a plant isoflavonoid that causes biliary atresia. Lorent K, Gong W, Koo KA, Waisbourd-Zinman O, Karjoo S, Zhao X, Sealy I, Kettleborough RN, Stemple DL, Windsor PA, Whittaker SJ, Porter JR, Wells RG, Pack M. Sci Transl Med. 2015 May 6;7(286):286ra67. doi: 10.1126/scitranslmed.aaa1652.
Micromechanical poroelastic finite element and shear-lag models of tendon predict large strain dependent Poisson’s ratios and fluid expulsion under tensile loading. Ahmadzadeh H, Freedman BR, Connizzo BK, Soslowsky LJ, Shenoy VB. Acta Biomater. 2015 Aug;22:83-91. doi: 10.1016/j.actbio.2015.04.035. Epub 2015 Apr 29.
The (dys)functional extracellular matrix. Freedman BR, Bade ND, Riggin CN, Zhang S, Haines PG, Ong KL, Janmey PA. Biochim Biophys Acta. 2015 Nov;1853(11 Pt B):3153-64. doi: 10.1016/j.bbamcr.2015.04.015. Epub 2015 Apr 27. Review.
DNA-damage-induced type I interferon promotes senescence and inhibits stem cell function. Yu Q, Katlinskaya YV, Carbone CJ, Zhao B, Katlinski KV, Zheng H, Guha M, Li N, Chen Q, Yang T, Lengner CJ, Greenberg RA, Johnson FB, Fuchs SY. Cell Rep. 2015 May 5;11(5):785-797. doi: 10.1016/j.celrep.2015.03.069. Epub 2015 Apr 23.
Physical chemistry and membrane properties of two phosphatidylinositol bisphosphate isomers. Slochower DR, Wang YH, Radhakrishnan R, Janmey PA. Phys Chem Chem Phys. 2015 May 21;17(19):12608-15. doi: 10.1039/c5cp00862j.
Prevalence and risk factors for patient-reported joint pain among patients with HIV/hepatitis C coinfection, hepatitis C monoinfection, and HIV monoinfection. Ogdie A, Pang WG, Forde KA, Samir BD, Mulugeta L, Chang KM, Kaplan DE, Amorosa VK, Kostman JR, Reddy RK, Schumacher RH, Lo Re V 3rd. BMC Musculoskelet Disord. 2015 Apr 19;16:93. doi: 10.1186/s12891-015-0552-z.
Flightless I interacts with NMMIIA to promote cell extension formation, which enables collagen remodeling. Arora PD, Wang Y, Bresnick A, Janmey PA, McCulloch CA. Mol Biol Cell. 2015 Jun 15;26(12):2279-97. doi: 10.1091/mbc.E14-11-1536. Epub 2015 Apr 15.
Does Massive Antigen Burden Allow Hepatic Viruses to Induce Regulatory T Cells and Their Tolerance and Persistence? Kaplan DE. Cell Mol Gastroenterol Hepatol. 2015 Apr 16;1(3):259-261. doi: 10.1016/j.jcmgh.2015.03.004. eCollection 2015 May. No abstract available.
Bactericidal activities of cathelicidin LL-37 and select cationic lipids against the hypervirulent Pseudomonas aeruginosa strain LESB58. Wnorowska U, Niemirowicz K, Myint M, Diamond SL, Wróblewska M, Savage PB, Janmey PA, Bucki R. Antimicrob Agents Chemother. 2015 Jul;59(7):3808-15. doi: 10.1128/AAC.00421-15. Epub 2015 Apr 13.
Vertical sleeve gastrectomy specimens have a high prevalence of unexpected histopathologic findings requiring additional clinical management. Raess PW, Baird-Howell M, Aggarwal R, Williams NN, Furth EE. Surg Obes Relat Dis. 2015 Sep-Oct;11(5):1020-3. doi: 10.1016/j.soard.2015.01.002. Epub 2015 Jan 9.
Analysis of cyst size and tumor markers in the management of pancreatic cysts: support for the original Sendai criteria. Hoffman RL, Gates JL, Kochman ML, Ginsberg GG, Ahmad NA, Chandrasekhara V, Furth EE, Vollmer CM, Drebin JA. J Am Coll Surg. 2015 Jun;220(6):1087-95. doi: 10.1016/j.jamcollsurg.2015.02.013. Epub 2015 Feb 21.
Single mammalian cells compensate for differences in cellular volume and DNA copy number through independent global transcriptional mechanisms. Padovan-Merhar O, Nair GP, Biaesch AG, Mayer A, Scarfone S, Foley SW, Wu AR, Churchman LS, Singh A, Raj A. Mol Cell. 2015 Apr 16;58(2):339-52. doi: 10.1016/j.molcel.2015.03.005. Epub 2015 Apr 9.
Segmental Transarterial Embolization in a Translational Rat Model of Hepatocellular Carcinoma. Gade TP, Hunt SJ, Harrison N, Nadolski GJ, Weber C, Pickup S, Furth EE, Schnall MD, Soulen MC, Celeste Simon M. J Vasc Interv Radiol. 2015 Aug;26(8):1229-37. doi: 10.1016/j.jvir.2015.02.006. Epub 2015 Apr 8.
Sendai and Fukuoka Consensus Guidelines Identify Advanced Neoplasia in Patients With Suspected Mucinous Cystic Neoplasms of the Pancreas. Kaimakliotis P, Riff B, Pourmand K, Chandrasekhara V, Furth EE, Siegelman ES, Drebin J, Vollmer CM, Kochman ML, Ginsberg GG, Ahmad NA. Clin Gastroenterol Hepatol. 2015 Oct;13(10):1808-15. doi: 10.1016/j.cgh.2015.03.017. Epub 2015 Mar 25.
Interactions and stress relaxation in monolayers of soft nanoparticles at fluid-fluid interfaces. Garbin V, Jenkins I, Sinno T, Crocker JC, Stebe KJ. Phys Rev Lett. 2015 Mar 13;114(10):108301. Epub 2015 Mar 9. Erratum in: Phys Rev Lett. 2015 Jul 10;115(2):029902.
Blood and immune cell engineering: Cytoskeletal contractility and nuclear rheology impact cell lineage and localization: Biophysical regulation of hematopoietic differentiation and trafficking. Shin JW, Discher DE. Bioessays. 2015 Jun;37(6):633-42. doi: 10.1002/bies.201400166. Epub 2015 Mar 23. Review.
Type III Collagen Directs Stromal Organization and Limits Metastasis in a Murine Model of Breast Cancer. Brisson BK, Mauldin EA, Lei W, Vogel LK, Power AM, Lo A, Dopkin D, Khanna C, Wells RG, Puré E, Volk SW. Am J Pathol. 2015 May;185(5):1471-86. doi: 10.1016/j.ajpath.2015.01.029. Epub 2015 Mar 17.
Cell motion and mechanobiology. Paluch EK, Discher DE. Mol Biol Cell. 2015 Mar 15;26(6):1011. doi: 10.1091/mbc.E14-12-1590. No abstract available.
Spindle assembly checkpoint acquisition at the mid-blastula transition. Zhang M, Kothari P, Lampson MA. PLoS One. 2015 Mar 5;10(3):e0119285. doi: 10.1371/journal.pone.0119285. eCollection 2015.
The Bicoid class homeodomain factors ceh-36/OTX and unc-30/PITX cooperate in C. elegans embryonic progenitor cells to regulate robust development. Walton T, Preston E, Nair G, Zacharias AL, Raj A, Murray JI. PLoS Genet. 2015 Mar 4;11(3):e1005003. doi: 10.1371/journal.pgen.1005003. eCollection 2015 Mar.
Monocyte-derived dendritic cells from cirrhotic patients retain similar capacity for maturation/activation and antigen presentation as those from healthy subjects. Tanoue S, Chang LY, Li Y, Kaplan DE. Cell Immunol. 2015 May;295(1):36-45. doi: 10.1016/j.cellimm.2015.02.008. Epub 2015 Feb 25.
Type I interferon controls propagation of long interspersed element-1. Yu Q, Carbone CJ, Katlinskaya YV, Zheng H, Zheng K, Luo M, Wang PJ, Greenberg RA, Fuchs SY. J Biol Chem. 2015 Apr 17;290(16):10191-9. doi: 10.1074/jbc.M114.612374. Epub 2015 Feb 25.
Opportunities in theoretical and computational polymeric materials and soft matter. Liu AJ, Grest GS, Marchetti MC, Grason GM, Robbins MO, Fredrickson GH, Rubinstein M, Olvera de la Cruz M. Soft Matter. 2015 Mar 28;11(12):2326-32. doi: 10.1039/c4sm02344g.
Heterogeneous CD8+ T cell migration in the lymph node in the absence of inflammation revealed by quantitative migration analysis. Banigan EJ, Harris TH, Christian DA, Hunter CA, Liu AJ. PLoS Comput Biol. 2015 Feb 18;11(2):e1004058. doi: 10.1371/journal.pcbi.1004058. eCollection 2015 Feb.
Disordered surface vibrations in jammed sphere packings. Sussman DM, Goodrich CP, Liu AJ, Nagel SR. Soft Matter. 2015 Apr 14;11(14):2745-51. doi: 10.1039/c4sm02905d.
Enhancement of Pulmozyme activity in purulent sputum by combination with poly-aspartic acid or gelsolin. Bucki R, Cruz K, Pogoda K, Eggert A, Chin L, Ferrin M, Imbesi G, Hadjiliadis D, Janmey PA. J Cyst Fibros. 2015 Sep;14(5):587-93. doi: 10.1016/j.jcf.2015.02.001. Epub 2015 Feb 13.
Induction of T-cell Immunity Overcomes Complete Resistance to PD-1 and CTLA-4 Blockade and Improves Survival in Pancreatic Carcinoma. Winograd R, Byrne KT, Evans RA, Odorizzi PM, Meyer AR, Bajor DL, Clendenin C, Stanger BZ, Furth EE, Wherry EJ, Vonderheide RH. Cancer Immunol Res. 2015 Apr;3(4):399-411. doi: 10.1158/2326-6066.CIR-14-0215. Epub 2015 Feb 12.
Biophysics of α-synuclein induced membrane remodelling. Shi Z, Sachs JN, Rhoades E, Baumgart T. Phys Chem Chem Phys. 2015 Jun 28;17(24):15561-8. doi: 10.1039/c4cp05883f. Epub 2015 Feb 10.
Comparative risk of recurrence of dysplasia and carcinoma after endoluminal eradication therapy of high-grade dysplasia versus intramucosal carcinoma in Barrett’s esophagus. Small AJ, Sutherland SE, Hightower JS, Guarner-Argente C, Furth EE, Kochman ML, Forde KA, Bewtra M, Falk GW, Ginsberg GG. Gastrointest Endosc. 2015 May;81(5):1158-66.e1-4. doi: 10.1016/j.gie.2014.10.029. Epub 2015 Jan 31.
DNA repair: Familiar ends with alternative endings. Cho NW, Greenberg RA. Nature. 2015 Feb 12;518(7538):174-6. doi: 10.1038/nature14200. Epub 2015 Feb 4. No abstract available.
Pancreaticoduodenectomy after remote liver and kidney transplantation for the treatment of intraductal papillary mucinous neoplasm. Hobbs RD, Ullery B, Furth E, Drebin J. Am Surg. 2015 Feb;81(2):E87-9. No abstract available.
MERIT40 deficiency expands hematopoietic stem cell pools by regulating thrombopoietin receptor signaling. Rozenova K, Jiang J, Donaghy R, Aressy B, Greenberg RA, Tong W. Blood. 2015 Mar 12;125(11):1730-8. doi: 10.1182/blood-2014-07-588145. Epub 2015 Jan 30.
Localization and abundance analysis of human lncRNAs at single-cell and single-molecule resolution. Cabili MN, Dunagin MC, McClanahan PD, Biaesch A, Padovan-Merhar O, Regev A, Rinn JL, Raj A. Genome Biol. 2015 Jan 29;16:20. doi: 10.1186/s13059-015-0586-4.
Changes in North Carolina maternal health service use and outcomes among medicaid-enrolled pregnant women during state budget cuts. Cilenti D, Kum HC, Wells R, Whitmire JT, Goyal RK, Hillemeier MM. J Public Health Manag Pract. 2015 Mar-Apr;21(2):208-13. doi: 10.1097/PHH.0000000000000118.
Comparison of Saccharomyces cerevisiae F-BAR domain structures reveals a conserved inositol phosphate binding site. Moravcevic K, Alvarado D, Schmitz KR, Kenniston JA, Mendrola JM, Ferguson KM, Lemmon MA. Structure. 2015 Feb 3;23(2):352-63. doi: 10.1016/j.str.2014.12.009. Epub 2015 Jan 22.
Whole-exome sequencing identifies somatic ATRX mutations in pheochromocytomas and paragangliomas. Fishbein L, Khare S, Wubbenhorst B, DeSloover D, D’Andrea K, Merrill S, Cho NW, Greenberg RA, Else T, Montone K, LiVolsi V, Fraker D, Daber R, Cohen DL, Nathanson KL. Nat Commun. 2015 Jan 21;6:6140. doi: 10.1038/ncomms7140.
Membrane tension and peripheral protein density mediate membrane shape transitions. Shi Z, Baumgart T. Nat Commun. 2015 Jan 8;6:5974. doi: 10.1038/ncomms6974.
Visualization of lncRNA by single-molecule fluorescence in situ hybridization. Dunagin M, Cabili MN, Rinn J, Raj A. Methods Mol Biol. 2015;1262:3-19. doi: 10.1007/978-1-4939-2253-6_1.
Phenomenology based multiscale models as tools to understand cell membrane and organelle morphologies. Ramakrishnan N, Radhakrishnan R. Adv Planar Lipid Bilayers Liposomes. 2015;22:129-175.
Biallelic mutations in BRCA1 cause a new Fanconi anemia subtype. Sawyer SL, Tian L, Kähkönen M, Schwartzentruber J, Kircher M; University of Washington Centre for Mendelian Genomics.; FORGE Canada Consortium., Majewski J, Dyment DA, Innes AM, Boycott KM, Moreau LA, Moilanen JS, Greenberg RA. Cancer Discov. 2015 Feb;5(2):135-42. doi: 10.1158/2159-8290.CD-14-1156. Epub 2014 Dec 3.
Cell rigidity and shape override CD47’s “self”-signaling in phagocytosis by hyperactivating myosin-II. Sosale NG, Rouhiparkouhi T, Bradshaw AM, Dimova R, Lipowsky R, Discher DE. Blood. 2015 Jan 15;125(3):542-52. doi: 10.1182/blood-2014-06-585299. Epub 2014 Nov 19.
Myosin-II repression favors pre/proplatelets but shear activation generates platelets and fails in macrothrombocytopenia. Spinler KR, Shin JW, Lambert MP, Discher DE. Blood. 2015 Jan 15;125(3):525-33. doi: 10.1182/blood-2014-05-576462. Epub 2014 Nov 13.
Inelastic behaviour of collagen networks in cell-matrix interactions and mechanosensation. Mohammadi H, Arora PD, Simmons CA, Janmey PA, McCulloch CA. J R Soc Interface. 2015 Jan 6;12(102):20141074. doi: 10.1098/rsif.2014.1074.
Esophageal epithelial cells acquire functional characteristics of activated myofibroblasts after undergoing an epithelial to mesenchymal transition. Muir AB, Dods K, Noah Y, Toltzis S, Chandramouleeswaran PM, Lee A, Benitez A, Bedenbaugh A, Falk GW, Wells RG, Nakagawa H, Wang ML. Exp Cell Res. 2015 Jan 1;330(1):102-10. doi: 10.1016/j.yexcr.2014.08.026. Epub 2014 Aug 27.
Effects of maternity care coordination on pregnancy outcomes: propensity-weighted analyses. Hillemeier MM, Domino ME, Wells R, Goyal RK, Kum HC, Cilenti D, Timothy Whitmire J, Basu A. Matern Child Health J. 2015 Jan;19(1):121-7. doi: 10.1007/s10995-014-1502-3.
Distinct features in natural history and outcomes of acute hepatitis C. Bunchorntavakul C, Jones LM, Kikuchi M, Valiga ME, Kaplan DE, Nunes FA, Aytaman A, Reddy KR, Chang KM. J Clin Gastroenterol. 2015 Apr;49(4):e31-40. doi: 10.1097/MCG.0000000000000076.